Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
phospho-p-T308,S473-AKT1 [plasma membrane]
Stable Identifier
R-DME-199430
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
Q8INB9
Locations in the PathwayBrowser
Expand all
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Platelet Aggregation (Plug Formation) (Drosophila melanogaster)
Integrin signaling (Drosophila melanogaster)
Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding (Drosophila melanogaster)
AKT1/PDK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-T308,S473-AKT1 [plasma membrane] (Drosophila melanogaster)
Metabolism (Drosophila melanogaster)
Metabolism of nitric oxide: NOS3 activation and regulation (Drosophila melanogaster)
eNOS activation (Drosophila melanogaster)
AKT1 binds eNOS complex via HSP90 (Drosophila melanogaster)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
phospho-p-T308,S473-AKT1 [plasma membrane] (Drosophila melanogaster)
AKT1 phosphorylates eNOS (Drosophila melanogaster)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
phospho-p-T308,S473-AKT1 [plasma membrane] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Integrin signaling (Drosophila melanogaster)
Integrin alpha IIb beta3 T779 phosphorylation blocks SHC binding (Drosophila melanogaster)
AKT1/PDK1 [plasma membrane] (Drosophila melanogaster)
phospho-p-T308,S473-AKT1 [plasma membrane] (Drosophila melanogaster)
MTOR signalling (Drosophila melanogaster)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
phospho-p-T308,S473-AKT1 [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
AKT1 binds eNOS complex via HSP90 (Drosophila melanogaster)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
phospho-p-T308,S473-AKT1 [plasma membrane] (Drosophila melanogaster)
AKT1 phosphorylates eNOS (Drosophila melanogaster)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
phospho-p-T308,S473-AKT1 [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q8INB9 Akt
Gene Names
Akt, Akt1, CG4006
Chain
chain:1-611
Reference Genes
BioGPS Gene:41957 Akt
CTD Gene:41957 Akt
KEGG Gene (Drosophila melanogaster):Dmel_CG4006 Akt
Monarch:41957 Akt
NCBI Gene:41957 Akt
Reference Transcript
RefSeq:NM_169707.2 Akt
RefSeq:NM_001300425.1 Akt
RefSeq:NM_169706.2 Akt
RefSeq:NM_001300424.1 Akt
RefSeq:NM_169705.2 Akt
Other Identifiers
141791_at
1639064_s_at
41957
GO:0000166
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0005938
GO:0006468
GO:0006629
GO:0006915
GO:0006979
GO:0007424
GO:0007427
GO:0007623
GO:0008284
GO:0008286
GO:0010884
GO:0010897
GO:0012501
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0022414
GO:0023052
GO:0030154
GO:0030307
GO:0031104
GO:0032869
GO:0034330
GO:0035206
GO:0035264
GO:0035331
GO:0035556
GO:0036211
GO:0040014
GO:0040018
GO:0042060
GO:0042632
GO:0043025
GO:0043066
GO:0043226
GO:0043491
GO:0043524
GO:0044319
GO:0045793
GO:0045886
GO:0046622
GO:0048010
GO:0048477
GO:0048680
GO:0048856
GO:0048870
GO:0050773
GO:0055088
GO:0060292
GO:0090278
GO:0106310
GO:0140096
GO:1901215
GO:1903688
GO:1904263
Participates
as a member of
AKT1/PDK1 [plasma membrane] (Drosophila melanogaster)
as a component of
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
phospho-p-T309,S474-AKT2 [nucleoplasm]
phospho-p-T305,S472-AKT3 [nucleoplasm]
phospho-p-T308,S473-AKT1 [nucleoplasm]
phospho-p-T305,S472-AKT3 [cytosol]
phospho-p-T309,S474-AKT2 [cytosol]
phospho-p-T308,S473-AKT1 [cytosol]
phospho-p-S474-AKT2 [plasma membrane]
phospho-p-S472-AKT3 [plasma membrane]
phospho-p-S473-AKT1 [plasma membrane]
AKT2 [plasma membrane]
AKT3 [plasma membrane]
AKT1 [plasma membrane]
AKT2 [cytosol]
AKT3 [cytosol]
AKT1 [cytosol]
phospho-p-T309-AKT2 [cytosol]
phospho-p-T305-AKT3 [cytosol]
phospho-p-T308-AKT1 [cytosol]
Activated DAkt1 [cytosol]
AKT1 [plasma membrane]
AKT1 [cytosol]
Inferred From
p-T308,S473-AKT1 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 308
Coordinate
308
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 473
Coordinate
473
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_732113.3
,
NP_732115.1
,
NP_732114.1
,
NP_001287354.1
,
NP_001287353.1
Flybase
FBgn0010379
IntEnz
2.7.11.1
PRO
Q8INB9
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VDE3 Q9VDE3
0.576
4
UniProt:P68198 UBIQ
0.499
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text