Reactome | PRKN [cytosol]

PRKN [cytosol]

Stable Identifier

R-DME-201579

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

Q7KTX7

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q7KTX7

Reference Genes

BioGPS Gene:40336

CTD Gene:40336

ENSEMBL:FBgn0041100

FlyBase:FBgn0041100

KEGG:dme:Dmel_CG10523

Monarch:40336

NCBI Gene:40336

UCSC:Q7KTX7

Reference Transcript

Other Identifiers

141474_at

1629967_s_at

40336

GO:0000151

GO:0000209

GO:0000266

GO:0000422

GO:0000423

GO:0001933

GO:0003824

GO:0004842

GO:0005515

GO:0005737

GO:0005739

GO:0005783

GO:0005794

GO:0005829

GO:0006511

GO:0006513

GO:0006914

GO:0006979

GO:0007005

GO:0007283

GO:0008270

GO:0008344

GO:0008345

GO:0009893

GO:0010637

GO:0010821

GO:0016567

GO:0016740

GO:0022414

GO:0030382

GO:0031624

GO:0032436

GO:0042981

GO:0043226

GO:0046329

GO:0046872

GO:0048078

GO:0048477

GO:0048856

GO:0051865

GO:0055069

GO:0061630

GO:0061734

GO:0070050

GO:0090141

GO:0140096

GO:1900407

GO:1901526

GO:1903599

GO:1904061

GO:1904457

Participates

as an input of

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)

as a component of

Other forms of this molecule

phospho-p-S65-PRKN [cytosol]

phospho-p-S9-PRKN [cytosol]

polyUb-PARK2 [cytosol]

Inferred From

PRKN [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_730601.1, NP_730600.1

ENSEMBL

FBpp0077974, FBtr0078319, FBtr0078318, FBpp0077975

IntEnz

2.3.2.31

PDB

2LWR, 2M48

Interactors (27)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q7YU24	10	MFN2 [mitochondrial outer membrane] (R-DME-992714-2) MFN1 [mitochondrial outer membrane] (R-DME-992745) Ub-MFN2 [mitochondrial outer membrane] (R-DME-9835010-2) Ub-MFN1 [mitochondrial outer membrane] (R-DME-9834985) K48polyUb-MFN2 [mitochondrial outer membrane] (R-DME-5205668-2) K48polyUb-MFN1 [mitochondrial outer membrane] (R-DME-5205679) K63polyUb-MFN1 [mitochondrial outer membrane] (R-DME-9834040) K63polyUb-MFN2 [mitochondrial outer membrane] (R-DME-9834043-2) p-S65-Ub:MFN2 [mitochondrial outer membrane] (R-DME-9834980-2) p-S65-Ub:MFN1 [mitochondrial outer membrane] (R-DME-9835008)	0.589	2
UniProt:Q9VVX6	3	Bet1 [Golgi membrane] (R-DME-6807743) Bet1 [transport vesicle] (R-DME-6808719) Bet1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-DME-5688142)	0.488	2
UniProt:Q9VEJ4	1	Dmel\CG5823 [cytosol] (R-DME-947637)	0.488	2
UniProt:Q9VPN0 Q9VPN0			0.488	2
UniProt:Q9VIL1 Q9VIL1			0.488	2
UniProt:Q7K087 Q7K087			0.488	2
UniProt:Q9VLL8 Q9VLL8			0.488	2
UniProt:Q9VMN4 Q9VMN4			0.488	2
UniProt:Q9VQT8 Q9VQT8			0.488	2
UniProt:Q9VPD4 Q9VPD4			0.488	2
UniProt:Q9W4B6	3	BcDNA:RE01432 [specific granule membrane] (R-DME-6800916) BcDNA:RE01432 [plasma membrane] (R-DME-6806275) BcDNA:RE01432 [azurophil granule membrane] (R-DME-6799141)	0.488	2
UniProt:Q9VD26 ZFPL1			0.488	2
UniProt:Q9W4B3 Q9W4B3			0.488	2
UniProt:Q8SYY7	20	Spn43Ad [extracellular region] (R-DME-374187-14) Spn43Ad [extracellular region] (R-DME-2022346-14) Spn43Ad [extracellular region] (R-DME-1998759-14) Spn43Ad [extracellular region] (R-DME-158296-14) Spn43Ad [endoplasmic reticulum lumen] (R-DME-8956709-14) Spn43Ad [endoplasmic reticulum lumen] (R-DME-8956731-14) Spn43Ad [endoplasmic reticulum lumen] (R-DME-8956773-14) phospho-Spn43Ad [endoplasmic reticulum lumen] (R-DME-8957069-14) phospho-Spn43Ad [endoplasmic reticulum lumen] (R-DME-8957062-14) phospho-Spn43Ad [endoplasmic reticulum lumen] (R-DME-8956982-14) Spn43Ad [extracellular region] (R-DME-5591085-14) Spn43Ad [extracellular region] (R-DME-4127459-14) Spn43Ad [ficolin-1-rich granule membrane] (R-DME-6803334-14) Spn43Ad [plasma membrane] (R-DME-6803371-14) Spn43Ad [secretory granule lumen] (R-DME-6801018-14) Spn43Ad [extracellular region] (R-DME-6806173-14) Spn43Ad [azurophil granule lumen] (R-DME-6799340-14) Spn43Ad [azurophil granule lumen] (R-DME-6798754-14) Spn43Ad [extracellular region] (R-DME-6806189-14) Spn43Ad [ficolin-1-rich granule lumen] (R-DME-6804783-14)	0.488	2
UniProt:O97172 U729			0.488	2
UniProt:Q8SX37	1	CDIPT [endoplasmic reticulum membrane] (R-DME-1498749)	0.488	2
UniProt:Q9V5Z7	7	Drip [transport vesicle membrane] (R-DME-432215-5) phospho-Drip [transport vesicle membrane] (R-DME-432222-5) Drip [plasma membrane] (R-DME-432026-5) Drip [plasma membrane] (R-DME-431733-5) phospho-Drip [plasma membrane] (R-DME-432231-5) Drip [plasma membrane] (R-DME-431738-5) Drip [plasma membrane] (R-DME-431700-5)	0.488	2
UniProt:Q8IQ76 Q8IQ76			0.488	2
UniProt:A1Z8Z3 A1Z8Z3			0.488	2
UniProt:Q9W4S5 Q9W4S5			0.488	2
UniProt:Q9W1K0 TM14			0.488	2
UniProt:Q8SYA4 Q8SYA4			0.488	2
UniProt:Q7K2P1 Q7K2P1			0.488	2
UniProt:Q0E985 Q0E985			0.488	2
UniProt:Q7JRF1 Q7JRF1			0.488	2
UniProt:Q8SY76 Q8SY76			0.488	2
UniProt:Q8MLR2 Q8MLR2			0.488	2

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