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Pdk1 [cytosol]
Stable Identifier
R-DME-202210
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
PDPK1, Q9W0V1
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to mechanical stimuli (Drosophila melanogaster)
Response of endothelial cells to shear stress (Drosophila melanogaster)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Drosophila melanogaster)
Phosphorylation of PDPK1 on serine-241 (Drosophila melanogaster)
Pdk1 [cytosol] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
GPVI-mediated activation cascade (Drosophila melanogaster)
PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)
Pdk1 [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Regulation of T cell activation by CD28 family (Drosophila melanogaster)
Co-stimulation by CD28 (Drosophila melanogaster)
CD28 dependent PI3K/Akt signaling (Drosophila melanogaster)
PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)
Pdk1 [cytosol] (Drosophila melanogaster)
TCR signaling (Drosophila melanogaster)
Downstream TCR signaling (Drosophila melanogaster)
Translocation of PDK1 to Plasma membrane (Drosophila melanogaster)
Pdk1 [cytosol] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
Role of LAT2/NTAL/LAB on calcium mobilization (Drosophila melanogaster)
Translocation of PDK1 to Plasma membrane (Drosophila melanogaster)
Pdk1 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
PDPK1 binds PIP2 (Drosophila melanogaster)
Pdk1 [cytosol] (Drosophila melanogaster)
PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)
Pdk1 [cytosol] (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G-protein beta:gamma signalling (Drosophila melanogaster)
G beta:gamma signalling through PI3Kgamma (Drosophila melanogaster)
PIP3 recruits PDK1 and AKT to the membrane (Drosophila melanogaster)
Pdk1 [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)
Pdk1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9W0V1 Pdk1
Gene Names
Pdk1, Pk61C, CG1210
Chain
chain:1-836
Reference Genes
BioGPS Gene:38017 Pdk1
KEGG:dme:Dmel_CG1210 Pdk1
Monarch:38017 Pdk1
NCBI Gene:38017 Pdk1
UCSC:Q9W0V1 Pdk1
Reference Transcript
RefSeq:NM_167793.3 Pdk1
RefSeq:NM_167792.3 Pdk1
RefSeq:NM_167795.3 Pdk1
RefSeq:NM_167794.3 Pdk1
RefSeq:NM_167789.2 Pdk1
RefSeq:NM_167790.3 Pdk1
RefSeq:NM_001274254.1 Pdk1
RefSeq:NM_167791.3 Pdk1
RefSeq:NM_080382.4 Pdk1
Other Identifiers
142677_s_at
1629078_s_at
38017
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004676
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006468
GO:0006915
GO:0007166
GO:0007283
GO:0008284
GO:0008286
GO:0009898
GO:0016301
GO:0016740
GO:0022414
GO:0030154
GO:0030295
GO:0030307
GO:0031594
GO:0034330
GO:0035556
GO:0040018
GO:0043066
GO:0043491
GO:0045793
GO:0046622
GO:0048638
GO:0051124
GO:0065008
GO:0098772
GO:0106310
GO:0140096
GO:1901701
GO:1904262
GO:1904263
Participates
as an input of
Phosphorylation of PDPK1 on serine-241 (Drosophila melanogaster)
PIP3 recruits PDK1 and AKT to the membrane (Drosophila melanogaster)
PDPK1 binds PIP2 (Drosophila melanogaster)
Translocation of PDK1 to Plasma membrane (Drosophila melanogaster)
PIP3 recruits PDPK1 to the membrane (Drosophila melanogaster)
Other forms of this molecule
PK61C [cytosol]
phospho-Pdk1 [cytosol]
Pdk1 [plasma membrane]
Inferred From
PDPK1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_525121.2
,
NP_728475.1
,
NP_728474.1
,
NP_001261183.1
,
NP_728470.1
,
NP_728476.1
,
NP_728472.1
,
NP_728473.1
,
NP_728471.2
ENSEMBL
FBpp0305420
,
FBtr0072464
,
FBtr0333218
,
FBpp0072366
,
FBgn0020386
FlyBase
FBgn0020386
PRO
Q9W0V1
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