Drosophila homolog of RAB6, Rab6, was isolated as the product of warthog (wrt) gene, identified in a genetic screen as a modifier of Notch eye phenotype. RAB6 is a GTP-ase that regulates trafficking through Golgi and trans-Golgi network (TGN).
Artavanis-Tsakonas, S, Purcell, K
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