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HDAC1 [nucleoplasm]
Stable Identifier
R-DME-205021
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
HDAC1, Q94517
Locations in the PathwayBrowser for interactor UniProt:Q24572
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
Mitotic G1 phase and G1/S transition (Drosophila melanogaster)
G0 and Early G1 (Drosophila melanogaster)
Recruitment of HDAC1 by p107 (RBL1) (Drosophila melanogaster)
HDAC1 [nucleoplasm] (Drosophila melanogaster)
Recruitment of HDAC1 by p130 (RBL2) (Drosophila melanogaster)
HDAC1 [nucleoplasm] (Drosophila melanogaster)
Developmental Biology (Drosophila melanogaster)
MITF-M-regulated melanocyte development (Drosophila melanogaster)
MITF-M-dependent gene expression (Drosophila melanogaster)
Regulation of MITF-M-dependent genes involved in apoptosis (Drosophila melanogaster)
HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Drosophila melanogaster)
HDAC1 [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Drosophila melanogaster)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Drosophila melanogaster)
TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Drosophila melanogaster)
HDAC1 [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Estrogen-dependent gene expression (Drosophila melanogaster)
FOXA1 and GATA3 bind to CCND1 promoter (Drosophila melanogaster)
HDAC1 [nucleoplasm] (Drosophila melanogaster)
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by TGF-beta Receptor Complex (Drosophila melanogaster)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Drosophila melanogaster)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Drosophila melanogaster)
TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Drosophila melanogaster)
HDAC1 [nucleoplasm] (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
TCF dependent signaling in response to WNT (Drosophila melanogaster)
Formation of the beta-catenin:TCF transactivating complex (Drosophila melanogaster)
Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Drosophila melanogaster)
HDAC1 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q94517 Rpd3
Gene Names
Rpd3, HDAC1, CG7471
Chain
chain:1-521
Reference Genes
BioGPS Gene:38565 Rpd3
KEGG Gene (Drosophila melanogaster):Dmel_CG7471 Rpd3
Monarch:38565 Rpd3
NCBI Gene:38565 Rpd3
Reference Transcript
RefSeq:NM_139661.4 Rpd3
Other Identifiers
153325_at
1633700_at
38565
GO:0000118
GO:0000122
GO:0000228
GO:0000785
GO:0003714
GO:0003824
GO:0004407
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005700
GO:0005705
GO:0005737
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006357
GO:0007350
GO:0008340
GO:0010629
GO:0016575
GO:0016580
GO:0016581
GO:0016787
GO:0017053
GO:0022414
GO:0023052
GO:0030154
GO:0030261
GO:0031061
GO:0031507
GO:0031523
GO:0035098
GO:0036211
GO:0043226
GO:0045129
GO:0045664
GO:0045814
GO:0045879
GO:0045892
GO:0046872
GO:0048477
GO:0048856
GO:0050771
GO:0061086
GO:0070822
GO:0070983
GO:0140096
GO:0140110
GO:0140297
GO:1902692
GO:2001229
Participates
as an input of
HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Drosophila melanogaster)
TGIF recruits HDAC1 to SMAD2/3:SMAD4 heterotrimer (Drosophila melanogaster)
Recruitment of HDAC1 by p107 (RBL1) (Drosophila melanogaster)
Recruitment of HDAC1 by p130 (RBL2) (Drosophila melanogaster)
as a component of
HDAC1:SIN3A:HINT1:MITF-M:BCL2 gene [nucleoplasm] (Drosophila melanogaster)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Drosophila melanogaster)
HDAC1 homodimer [nucleoplasm] (Drosophila melanogaster)
TLE:HDAC1 [nucleoplasm] (Drosophila melanogaster)
TLE1:HDAC1 [nucleoplasm] (Drosophila melanogaster)
p-2S-SMAD2/3:SMAD4:TGIF:HDAC1 [nucleoplasm] (Drosophila melanogaster)
HDAC1:RBL1:E2F4:TFDP1,TFDP2 [nucleoplasm] (Drosophila melanogaster)
HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2 [nucleoplasm] (Drosophila melanogaster)
CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] (Drosophila melanogaster)
HDAC1:HDAC2 [nucleoplasm] (Drosophila melanogaster)
as a member of
Histone deacetylase [nucleoplasm] (Drosophila melanogaster)
HDAC [nucleoplasm] (Drosophila melanogaster)
as an output of
Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Drosophila melanogaster)
FOXA1 and GATA3 bind to CCND1 promoter (Drosophila melanogaster)
Other forms of this molecule
RPD3 [nucleoplasm]
HDAC1 [nucleoplasm]
Inferred From
HDAC1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_647918.2
Flybase
FBgn0015805
IntEnz
3.5.1.98
PRO
Q94517
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q24338 ESC
0.803
11
UniProt:P42124
1
E(z) [nucleoplasm]
(R-DME-212298)
0.783
9
UniProt:Q24572
1
Caf1-55 [nucleoplasm]
(R-DME-212223)
0.688
4
UniProt:O97159
2
CHD4 [nucleoplasm]
(R-DME-3702078-2)
CHD3 [nucleoplasm]
(R-DME-4657012-2)
0.597
5
UniProt:Q24459 PCL
0.558
5
UniProt:P45975
1
SUV39H1 [nucleoplasm]
(R-DME-427517)
0.544
2
UniProt:A1Z9E2
1
mip120 [nucleoplasm]
(R-DME-389103)
0.499
2
UniProt:Q9NHX6 Gug
1
GUG [cytosol]
(R-DME-350975)
0.463
2
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