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DCO [cytosol]
Stable Identifier
R-DME-205729
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Circadian Clock pathway (Drosophila melanogaster)
Degradation of PER (Drosophila melanogaster)
Cytosolic PER is degraded by the 26S proteasome (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
SLMB:UBI-P63E:Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
SLMB binds phosphorylated cytosolic PER, facilitating its ubiquitination (Drosophila melanogaster)
Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
SLMB:UBI-P63E:Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Dephosphorylation of PER (Drosophila melanogaster)
Cytosolic PP2A dephosphorylates phosphorylated PER complexed with DCO (Drosophila melanogaster)
PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Cytosolic PP2A dephosphorylates phosphorylated PER complexed with TIM and DCO (Drosophila melanogaster)
TIM:PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
TIM:Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Dephosphorylation of TIM (Drosophila melanogaster)
PP1 binds to phosphorylated TIM in complex with PER (Drosophila melanogaster)
PP1:Phospho TIM:Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho TIM:Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
PP1 dephosphorylates phosphorylated TIM in the complex with PER and DCO (Drosophila melanogaster)
PP1:Phospho TIM:Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
TIM:Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Nuclear import of PER and TIM (Drosophila melanogaster)
Phosphorylated PER transports from the cytosol to the nucleus (Drosophila melanogaster)
Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylation of PER and TIM (Drosophila melanogaster)
CRY is phosphorylated by SGG (Drosophila melanogaster)
Phospho AXN:Phospho APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
PER binds to DCO (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
PER is phosphorylated by DCO (Drosophila melanogaster)
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylated PER binds to TIM (Drosophila melanogaster)
Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
TIM:Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylated PER is phosphorylated by CK2 (Drosophila melanogaster)
TIM:Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
TIM:Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylated TIM:PER heterodimer dissociate (Drosophila melanogaster)
Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho TIM:Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
TIM is phosphorylated by CK2 (Drosophila melanogaster)
Phospho TIM:Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
TIM:Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Hedgehog pathway (Drosophila melanogaster)
N-HH ligand bound to PTC receptor complex (Drosophila melanogaster)
Activation of SMO (Drosophila melanogaster)
Phosphorylation of SMO (Drosophila melanogaster)
Phosphorylation of SMO by CKIalpha (Drosophila melanogaster)
ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
N-HH ligand not bound to PTC receptor complex (Drosophila melanogaster)
Assembly of the CI containing complexes (Drosophila melanogaster)
Formation of the 'scaffold complex' (Drosophila melanogaster)
COS:CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylation of CI (Drosophila melanogaster)
Further phosphorylation of CI by CKIalphaepsilon (Drosophila melanogaster)
CKIalphaepsilon [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (13 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (16 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylation of CI by CKIalphaepsilon (CKIalpha/DCO) (Drosophila melanogaster)
CKIalphaepsilon [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (11 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (3 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylation of CI by PKA-C1 (Drosophila melanogaster)
COS:CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (3 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylation of CI by SGG (Drosophila melanogaster)
COS:Phospho (11 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (13 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho AXN:Phospho APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Ubiquitination and proteolysis of phosphorylated CI (Drosophila melanogaster)
SLMB binds to and ubiquitinates phosphorylated CI (Drosophila melanogaster)
COS:Phospho (16 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:COS:Phospho (16 sites) CI:UBI-P63E:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (16 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Ubiquitinated and phosphorylated CI is partially degraded by the proteasome complex (Drosophila melanogaster)
COS:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:COS:Phospho (16 sites) CI:UBI-P63E:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (16 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Hippo/Warts pathway (Drosophila melanogaster)
DS ligand bound to FT receptor (Drosophila melanogaster)
LFT binds to FT and DS (Drosophila melanogaster)
DS:Phospho FT:DCO [plasma membrane] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
LFT:DS:Phospho FT:LFT:DCO [plasma membrane] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Subcellular localisation of D (Drosophila melanogaster)
DCO binds to FT (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
DS:FT:DCO [plasma membrane] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
FT is phosphorylated by DCO (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
DS:FT:DCO [plasma membrane] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
DS:Phospho FT:DCO [plasma membrane] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho FT reduces D accumulation at the plasma membrane (Drosophila melanogaster)
DS:Phospho FT:DCO [plasma membrane] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Wingless pathway (Drosophila melanogaster)
WG ligand bound to FZ receptors (Drosophila melanogaster)
Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM (Drosophila melanogaster)
Destabilisation and degradation of AXN in the 'destruction complex' (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:AXN:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Disassembly of the destabilised 'destruction complex' (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Inhibition of SGG results in the dephosphorylation of the 'destruction complex' by PP2A and release of ARM (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:AXN:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:Phospho ARM (4 sites):DSH:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Membrane recruitment of DSH to FZ and AXN to phosphorylated ARR (Drosophila melanogaster)
Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:Phospho ARM (4 sites):DSH:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
WG ligand not bound to FZ receptors (Drosophila melanogaster)
Assembly of the 'destruction complex' (Drosophila melanogaster)
ARM binds to APC and AXN in the 'destruction complex' (Drosophila melanogaster)
ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Formation of the 'destruction complex' (Drosophila melanogaster)
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylation of ARM (Drosophila melanogaster)
Further phosphorylation of ARM by SGG (Drosophila melanogaster)
Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylation of ARM by CKIalpha (Drosophila melanogaster)
ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylation of AXN and APC (Drosophila melanogaster)
Further phosphorylation of APC by DCO (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho (3 sites) AXN:Phospho (2 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho (3 sites) AXN:Phospho (5 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Further phosphorylation of APC by SGG (Drosophila melanogaster)
Phospho (3 sites) AXN:Phospho (5 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylation of AXN and APC by DCO (Drosophila melanogaster)
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho AXN:Phospho APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phosphorylation of AXN and APC by SGG (Drosophila melanogaster)
Phospho (3 sites) AXN:Phospho (2 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Phospho AXN:Phospho APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
Ubiquitination and degradation of phosphorylated ARM (Drosophila melanogaster)
Dissociation of free ubiquitinated and phosphorylated ARM from SLMB and the 'destruction complex' (Drosophila melanogaster)
Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
SLMB binds to phosphorylated ARM to form the 'destruction complex' (Drosophila melanogaster)
Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DCO [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:O76324 dco
Gene Names
dco, dbt, CG2048
Chain
chain:1-440
Reference Genes
BioGPS Gene:43673 dco
CTD Gene:43673 dco
KEGG Gene (Drosophila melanogaster):Dmel_CG2048 dco
Monarch:43673 dco
NCBI Gene:43673 dco
UCSC:O76324 dco
Reference Transcript
RefSeq:NM_170535.2 dco
RefSeq:NM_170536.3 dco
RefSeq:NM_001276203.1 dco
RefSeq:NM_079863.3 dco
Other Identifiers
143635_at
153528_at
1624447_s_at
1638726_at
43673
GO:0000166
GO:0001933
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0006468
GO:0006897
GO:0007010
GO:0007154
GO:0007165
GO:0007446
GO:0007555
GO:0007623
GO:0012501
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0023052
GO:0030163
GO:0030177
GO:0030307
GO:0030838
GO:0032436
GO:0035332
GO:0036211
GO:0042752
GO:0043066
GO:0043226
GO:0044297
GO:0045475
GO:0045732
GO:0045879
GO:0045880
GO:0046777
GO:0048148
GO:0048511
GO:0048856
GO:0050886
GO:0051781
GO:0065003
GO:0071482
GO:0090175
GO:0090263
GO:0106310
GO:0140096
Participates
as a component of
Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
Phospho ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
Phospho (3 sites) AXN:Phospho (5 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
Phospho (3 sites) AXN:Phospho (2 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
DS:FT:DCO [plasma membrane] (Drosophila melanogaster)
LFT:DS:Phospho FT:LFT:DCO [plasma membrane] (Drosophila melanogaster)
DS:Phospho FT:DCO [plasma membrane] (Drosophila melanogaster)
PP1:Phospho TIM:Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
TIM:PER:DCO [cytosol] (Drosophila melanogaster)
SLMB:UBI-P63E:Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
PER:DCO [cytosol] (Drosophila melanogaster)
AXN:APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
TIM:Phospho (multi-site 1) PER:DCO [cytosol] (Drosophila melanogaster)
TIM:Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
Phospho TIM:Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
Phospho (multi-site 2) PER:DCO [cytosol] (Drosophila melanogaster)
ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
COS:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (3 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (11 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
Phospho AXN:Phospho APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
COS:Phospho (13 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
COS:Phospho (16 sites) CI:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
as an output of
Disassembly of the destabilised 'destruction complex' (Drosophila melanogaster)
Cytosolic PER is degraded by the 26S proteasome (Drosophila melanogaster)
as an input of
Formation of the 'destruction complex' (Drosophila melanogaster)
DCO binds to FT (Drosophila melanogaster)
PER binds to DCO (Drosophila melanogaster)
Formation of the 'scaffold complex' (Drosophila melanogaster)
as a member of
CKIalphaepsilon [cytosol] (Drosophila melanogaster)
Other forms of this molecule
DCO [nucleoplasm]
CSNK1E [nucleoplasm]
CSNK1E [cytosol]
Cross References
RefSeq
NP_524602.1
,
NP_733415.1
,
NP_001263132.1
,
NP_733414.1
Flybase
FBgn0002413
PRO
O76324
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