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Go!
EFF [cytosol]
Stable Identifier
R-DME-205773
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Hedgehog pathway (Drosophila melanogaster)
N-HH ligand not bound to PTC receptor complex (Drosophila melanogaster)
Ubiquitination and proteolysis of phosphorylated CI (Drosophila melanogaster)
SLMB binds to and ubiquitinates phosphorylated CI (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF [cytosol] (Drosophila melanogaster)
EFF [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:COS:Phospho (16 sites) CI:UBI-P63E:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF [cytosol] (Drosophila melanogaster)
EFF [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF [cytosol] (Drosophila melanogaster)
EFF [cytosol] (Drosophila melanogaster)
Ubiquitinated and phosphorylated CI is partially degraded by the proteasome complex (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF [cytosol] (Drosophila melanogaster)
EFF [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:COS:Phospho (16 sites) CI:UBI-P63E:FU:PKA-C1:SGG:CKIalpha:DCO [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF [cytosol] (Drosophila melanogaster)
EFF [cytosol] (Drosophila melanogaster)
Wingless pathway (Drosophila melanogaster)
WG ligand not bound to FZ receptors (Drosophila melanogaster)
Ubiquitination and degradation of phosphorylated ARM (Drosophila melanogaster)
Dissociation of free ubiquitinated and phosphorylated ARM from SLMB and the 'destruction complex' (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF [cytosol] (Drosophila melanogaster)
EFF [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF [cytosol] (Drosophila melanogaster)
EFF [cytosol] (Drosophila melanogaster)
SLMB binds to phosphorylated ARM to form the 'destruction complex' (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF [cytosol] (Drosophila melanogaster)
EFF [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF:Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] (Drosophila melanogaster)
SLMB:SKPA:LIN19:ROC1A:EFF [cytosol] (Drosophila melanogaster)
EFF [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P25867 eff
Gene Names
eff, UbcD1, CG7425
Chain
chain:1-147
Reference Genes
BioGPS Gene:41785 eff
KEGG Gene (Drosophila melanogaster):Dmel_CG7425 eff
Monarch:41785 eff
NCBI Gene:41785 eff
Reference Transcript
RefSeq:NM_001275650.1 eff
RefSeq:NM_001275649.1 eff
RefSeq:NM_169601.2 eff
Other Identifiers
143638_at
1636436_at
41785
GO:0000151
GO:0000166
GO:0000209
GO:0000278
GO:0001745
GO:0001751
GO:0002376
GO:0003824
GO:0005515
GO:0005524
GO:0005634
GO:0005829
GO:0006511
GO:0007049
GO:0007140
GO:0016322
GO:0016567
GO:0016740
GO:0022414
GO:0023052
GO:0030154
GO:0030163
GO:0030718
GO:0031145
GO:0031625
GO:0031647
GO:0036211
GO:0043226
GO:0045676
GO:0045879
GO:0048132
GO:0048856
GO:0051276
GO:0051301
GO:0051321
GO:0061057
GO:0061631
GO:0097039
GO:0098542
GO:0140013
GO:0140096
Participates
as a component of
SLMB:SKPA:LIN19:ROC1A:EFF [cytosol] (Drosophila melanogaster)
Other forms of this molecule
eff [cytosol]
eff [nucleoplasm]
eff [cytosol]
Cross References
RefSeq
NP_001262578.1
,
NP_731941.1
,
NP_001262579.1
Flybase
FBgn0011217
PRO
P25867
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:A1Z9I6
1
anon-EST:GressD1 [cytosol]
(R-DME-975976)
0.621
3
UniProt:Q9VHI7
2
Iru [cytosol]
(R-DME-8850904)
Iru [cytosol]
(R-DME-8851642)
0.488
2
UniProt:Q9VP20
2
phospho-Mkrn1 [cytosol]
(R-DME-8948758)
Mkrn1 [cytosol]
(R-DME-976042)
0.488
2
UniProt:Q9VNB2 Q9VNB2
0.488
2
UniProt:Q8T3Y0
1
SIAH2 [cytosol]
(R-DME-374566-2)
0.488
2
UniProt:Q7JUV6 Q7JUV6
0.488
2
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