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UPD2 [extracellular region]
Stable Identifier
R-DME-205798
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
JAK/STAT pathway (Drosophila melanogaster)
Dephosphorylation by PTP61F phosphatases (Drosophila melanogaster)
Phosphorylated HOP is dephosphorylated by PTP61F isoform 1 (Drosophila melanogaster)
HOP:DOME:UPD:DOME:HOP [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
Phospho HOP:DOME:UPD:DOME:Phospho HOP [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
Formation of the activated STAT92E dimer and transport to the nucleus (Drosophila melanogaster)
Phosphorylated STAT92E dissociates from HOP and DOME and dimerises (Drosophila melanogaster)
Phospho HOP:Phospho DOME:UPD:Phospho DOME:Phospho HOP [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
Phospho STAT92E:Phospho HOP:Phospho DOME:UPD:Phospho DOME:Phospho HOP:Phospho STAT92E [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
STAT92E binds to phosphorylated HOP and phosphorylated DOME (Drosophila melanogaster)
Phospho HOP:Phospho DOME:UPD:Phospho DOME:Phospho HOP [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
STAT92E:Phospho HOP:Phospho DOME:UPD:Phospho DOME:Phospho HOP:STAT92E [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
STAT92E is phosphorylated by phosphorylated HOP (Drosophila melanogaster)
Phospho STAT92E:Phospho HOP:Phospho DOME:UPD:Phospho DOME:Phospho HOP:Phospho STAT92E [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
STAT92E:Phospho HOP:Phospho DOME:UPD:Phospho DOME:Phospho HOP:STAT92E [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
Formation of the activated receptor complex (Drosophila melanogaster)
Activated HOP is autophosphorylated and/or transphosphorylated (Drosophila melanogaster)
HOP:DOME:UPD:DOME:HOP [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
Phospho HOP:DOME:UPD:DOME:Phospho HOP [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
Phosphorylated HOP phosphorylates DOME (Drosophila melanogaster)
Phospho HOP:DOME:UPD:DOME:Phospho HOP [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
Phospho HOP:Phospho DOME:UPD:Phospho DOME:Phospho HOP [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
UPD ligand binds to the HOP:DOME:DOME:HOP complex and activates HOP (Drosophila melanogaster)
HOP:DOME:UPD:DOME:HOP [plasma membrane] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
UPD [extracellular region] (Drosophila melanogaster)
UPD2 [extracellular region] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VWX2 upd2
Gene Names
upd2, Dmel_CG5988
Reference Transcript
RefSeq:NM_133049.4 upd2
Other Identifiers
145286_at
1623718_at
32805
GO:0001700
GO:0005125
GO:0005576
GO:0005615
GO:0005768
GO:0005769
GO:0005770
GO:0007259
GO:0007379
GO:0010884
GO:0022600
GO:0023052
GO:0031410
GO:0038001
GO:0040018
GO:0042246
GO:0043226
GO:0048018
GO:0048856
GO:0060729
GO:0098772
Participates
as a member of
UPD [extracellular region] (Drosophila melanogaster)
Cross References
RefSeq
NP_573277.2
Flybase
FBgn0030904
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