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DL [cytosol]
Stable Identifier
R-DME-206011
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Toll pathway (Drosophila melanogaster)
Degradation of NF-kappa-B inhibitor, CACT (Drosophila melanogaster)
DL and DIF homodimers bind to TUB and phosphorylated PLL in the TL receptor 'signalling complex' (Drosophila melanogaster)
DL dimer binds to TUB and phosphorylated PLL in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
DL dimer:CACT [cytosol] (Drosophila melanogaster)
DL dimer [cytosol] (Drosophila melanogaster)
DL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane] (Drosophila melanogaster)
DL dimer:CACT [cytosol] (Drosophila melanogaster)
DL dimer [cytosol] (Drosophila melanogaster)
DL [cytosol] (Drosophila melanogaster)
DL/DIF dimer binds to TUB and phosphorylated PLL in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
DL/DIF dimer:CACT [cytosol] (Drosophila melanogaster)
DL/DIF dimer [cytosol] (Drosophila melanogaster)
DL dimer [cytosol] (Drosophila melanogaster)
DL [cytosol] (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL:DL/DIF dimer:CACT [plasma membrane] (Drosophila melanogaster)
DL/DIF dimer:CACT [cytosol] (Drosophila melanogaster)
DL/DIF dimer [cytosol] (Drosophila melanogaster)
DL dimer [cytosol] (Drosophila melanogaster)
DL [cytosol] (Drosophila melanogaster)
DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' (Drosophila melanogaster)
CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:PLL:MYD88:TUB:WEK dimer:MYD88:TUB:Phospho PLL:DL dimer:CACT [plasma membrane] (Drosophila melanogaster)
DL dimer:CACT [cytosol] (Drosophila melanogaster)
DL dimer [cytosol] (Drosophila melanogaster)
DL [cytosol] (Drosophila melanogaster)
CACT and DL/DIF dimer are phosphorylated in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
SPZ dimer:TL dimer:SPZ dimer:MYD88:TUB:Phospho PLL:DL/DIF dimer:CACT [plasma membrane] (Drosophila melanogaster)
DL/DIF dimer:CACT [cytosol] (Drosophila melanogaster)
DL/DIF dimer [cytosol] (Drosophila melanogaster)
DL dimer [cytosol] (Drosophila melanogaster)
DL [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P15330 dl
Gene Names
dl, CG6667
Chain
chain:1-999
Reference Genes
BioGPS Gene:35047 dl
CTD Gene:35047 dl
KEGG Gene (Drosophila melanogaster):Dmel_CG6667 dl
Monarch:35047 dl
NCBI Gene:35047 dl
UCSC:P15330 dl
Reference Transcript
RefSeq:NM_165219.2 dl
RefSeq:NM_165217.3 dl
RefSeq:NM_001169529.1 dl
RefSeq:NM_165218.3 dl
RefSeq:NM_001169530.1 dl
RefSeq:NM_001299085.1 dl
Other Identifiers
143125_at
1623415_at
35047
GO:0000977
GO:0000978
GO:0000981
GO:0001228
GO:0002225
GO:0002376
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006955
GO:0007249
GO:0007399
GO:0008063
GO:0009605
GO:0009950
GO:0009953
GO:0010604
GO:0023052
GO:0030154
GO:0031594
GO:0034097
GO:0035006
GO:0035206
GO:0035208
GO:0038061
GO:0042802
GO:0043226
GO:0043565
GO:0045087
GO:0045612
GO:0045944
GO:0048468
GO:0048731
GO:0048856
GO:0048935
GO:0051173
GO:0070379
GO:0071212
GO:0098542
GO:0140110
GO:0140297
Participates
as a component of
DL dimer [cytosol] (Drosophila melanogaster)
Other forms of this molecule
dl [nucleoplasm]
dl [cytosol]
dl [cytosol]
dl [cytosol]
dl [nucleoplasm]
dl [nucleoplasm]
phospho-dl [nucleoplasm]
dl [nucleoplasm]
phospho-dl [nucleoplasm]
dl [nucleoplasm]
Phospho DL [nucleoplasm]
Phospho DL [cytosol]
Cross References
RefSeq
NP_724053.1
,
NP_001163000.1
,
NP_001286014.1
,
NP_001163001.1
,
NP_724052.1
,
NP_724054.1
Flybase
FBgn0260632
PRO
P15330
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q03017 cact
6
CACT [cytosol]
(R-DME-205871)
Phospho CACT [cytosol]
(R-DME-205886)
cact [nucleoplasm]
(R-DME-4656929)
phospho-cact [cytosol]
(R-DME-1168581)
phospho-cact [cytosol]
(R-DME-177677)
cact [cytosol]
(R-DME-168151)
0.745
7
UniProt:P15330 dl
13
dl [nucleoplasm]
(R-DME-177676)
dl [cytosol]
(R-DME-168172)
dl [cytosol]
(R-DME-5607652)
dl [cytosol]
(R-DME-1168579)
dl [nucleoplasm]
(R-DME-1168585)
dl [nucleoplasm]
(R-DME-4755466)
phospho-dl [nucleoplasm]
(R-DME-5624468)
dl [nucleoplasm]
(R-DME-5607656)
phospho-dl [nucleoplasm]
(R-DME-5660642)
dl [nucleoplasm]
(R-DME-8865233)
Phospho DL [nucleoplasm]
(R-DME-214731)
Phospho DL [cytosol]
(R-DME-214732)
DL [cytosol]
(R-DME-206011)
0.656
3
UniProt:Q9W1A4
1
tamo [cytosol]
(R-DME-9796351)
0.625
4
UniProt:P22812 tub
1
TUB [cytosol]
(R-DME-206155)
0.61
4
UniProt:Q05652 pll
11
Phospho PLL [cytosol]
(R-DME-206109)
PLL [cytosol]
(R-DME-206070)
phospho-K63polyUb-hp-IRAK1 [endosome membrane]
(R-DME-975112)
phospho-K63polyUb-hp-IRAK1 [cytosol]
(R-DME-451565)
phospho-p-IRAK2 [endosome membrane]
(R-DME-975187)
phospho-p-2S,S376,T,T209,T387-IRAK1 [endosome membrane]
(R-DME-975157)
phospho-p-2S,S376,T,T209,T387-IRAK1 [plasma membrane]
(R-DME-937011)
phospho-p-IRAK2 [plasma membrane]
(R-DME-936949)
phospho-p-2S,S376,T,T209,T387-IRAK1 [cytosol]
(R-DME-446682)
phospho-p-IRAK2 [cytosol]
(R-DME-446636)
IRAK4 [cytosol]
(R-DME-166081)
0.502
3
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