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DOME [plasma membrane]
Stable Identifier
R-DME-206172
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
JAK/STAT pathway (Drosophila melanogaster)
Dephosphorylation by PTP61F phosphatases (Drosophila melanogaster)
Phosphorylated HOP is dephosphorylated by PTP61F isoform 1 (Drosophila melanogaster)
HOP:DOME:UPD:DOME:HOP [plasma membrane] (Drosophila melanogaster)
DOME [plasma membrane] (Drosophila melanogaster)
Phospho HOP:DOME:UPD:DOME:Phospho HOP [plasma membrane] (Drosophila melanogaster)
DOME [plasma membrane] (Drosophila melanogaster)
Formation of the activated receptor complex (Drosophila melanogaster)
Activated HOP is autophosphorylated and/or transphosphorylated (Drosophila melanogaster)
HOP:DOME:UPD:DOME:HOP [plasma membrane] (Drosophila melanogaster)
DOME [plasma membrane] (Drosophila melanogaster)
Phospho HOP:DOME:UPD:DOME:Phospho HOP [plasma membrane] (Drosophila melanogaster)
DOME [plasma membrane] (Drosophila melanogaster)
DOME:HOP complex forms a dimer at the plasma membrane (Drosophila melanogaster)
HOP:DOME [plasma membrane] (Drosophila melanogaster)
DOME [plasma membrane] (Drosophila melanogaster)
HOP:DOME:DOME:HOP [plasma membrane] (Drosophila melanogaster)
DOME [plasma membrane] (Drosophila melanogaster)
Phosphorylated HOP phosphorylates DOME (Drosophila melanogaster)
Phospho HOP:DOME:UPD:DOME:Phospho HOP [plasma membrane] (Drosophila melanogaster)
DOME [plasma membrane] (Drosophila melanogaster)
Tyrosine kinase Hopscotch (HOP) binds to the transmembrane cytokine receptor Domeless (DOME) to form the HOP:DOME complex (Drosophila melanogaster)
DOME [plasma membrane] (Drosophila melanogaster)
HOP:DOME [plasma membrane] (Drosophila melanogaster)
DOME [plasma membrane] (Drosophila melanogaster)
UPD ligand binds to the HOP:DOME:DOME:HOP complex and activates HOP (Drosophila melanogaster)
HOP:DOME:DOME:HOP [plasma membrane] (Drosophila melanogaster)
DOME [plasma membrane] (Drosophila melanogaster)
HOP:DOME:UPD:DOME:HOP [plasma membrane] (Drosophila melanogaster)
DOME [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VWE0 dome
Gene Names
dome, CG14226
Chain
signal peptide:1-23, chain:24-1282
Reference Genes
BioGPS Gene:32976 dome
CTD Gene:32976 dome
KEGG Gene (Drosophila melanogaster):Dmel_CG14226 dome
Monarch:32976 dome
NCBI Gene:32976 dome
Reference Transcript
RefSeq:NM_078688.3 dome
Other Identifiers
142932_at
1632381_at
32976
GO:0001745
GO:0004896
GO:0005515
GO:0005886
GO:0007259
GO:0007298
GO:0007350
GO:0007424
GO:0007442
GO:0007472
GO:0007616
GO:0008284
GO:0016020
GO:0016324
GO:0016327
GO:0019221
GO:0022414
GO:0023052
GO:0030154
GO:0042246
GO:0045475
GO:0046982
GO:0048856
GO:0048870
GO:0050829
GO:0050877
GO:0060089
GO:0071907
GO:0097677
GO:0097678
GO:0098542
GO:1990782
Participates
as an input of
Tyrosine kinase Hopscotch (HOP) binds to the transmembrane cytokine receptor Domeless (DOME) to form the HOP:DOME complex (Drosophila melanogaster)
as a component of
HOP:DOME [plasma membrane] (Drosophila melanogaster)
HOP:DOME:DOME:HOP [plasma membrane] (Drosophila melanogaster)
HOP:DOME:UPD:DOME:HOP [plasma membrane] (Drosophila melanogaster)
Phospho HOP:DOME:UPD:DOME:Phospho HOP [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
Phospho DOME [plasma membrane]
Cross References
RefSeq
NP_523412.1
Flybase
FBgn0043903
PRO
Q9VWE0
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VWE1 Q9VWE1
0.527
4
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