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FZ [plasma membrane]
Stable Identifier
R-DME-206546
Type
Set [DefinedSet]
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Drosophila signaling pathways (Drosophila melanogaster)
Wingless pathway (Drosophila melanogaster)
WG ligand bound to FZ receptors (Drosophila melanogaster)
Assembly of receptor complex (Drosophila melanogaster)
Membrane-bound GISH binds to ARR receptor complex (Drosophila melanogaster)
WG:FZ:ARR [plasma membrane] (Drosophila melanogaster)
WG:FZ [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
WG:FZ:ARR:GISH [plasma membrane] (Drosophila melanogaster)
WG:FZ:ARR [plasma membrane] (Drosophila melanogaster)
WG:FZ [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
Phosphorylation of ARR (Drosophila melanogaster)
GISH further phosphorylates ARR in the receptor complex (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho ARR:GISH [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
Membrane localised SGG phosphorylates ARR (Drosophila melanogaster)
WG:FZ:ARR:GISH [plasma membrane] (Drosophila melanogaster)
WG:FZ:ARR [plasma membrane] (Drosophila melanogaster)
WG:FZ [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho ARR:GISH [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
WG, FZ and ARR bind to each other (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
WG:FZ:ARR [plasma membrane] (Drosophila melanogaster)
WG:FZ [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
Recruitment of the 'destruction complex' to the receptor complex, the degradation of AXN and release of ARM (Drosophila melanogaster)
Destabilisation and degradation of AXN in the 'destruction complex' (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:AXN:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
Disassembly of the destabilised 'destruction complex' (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
Inhibition of SGG results in the dephosphorylation of the 'destruction complex' by PP2A and release of ARM (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:DSH:AXN:APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:Phospho ARM (4 sites):DSH:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
Membrane recruitment of DSH to FZ and AXN to phosphorylated ARR (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH:Phospho ARM (4 sites):DSH:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH [plasma membrane] (Drosophila melanogaster)
FZ [plasma membrane] (Drosophila melanogaster)
Participants
members
FZ [plasma membrane]
(Drosophila melanogaster)
FZ2 [plasma membrane]
(Drosophila melanogaster)
Participates
as an input of
WG, FZ and ARR bind to each other (Drosophila melanogaster)
as a component of
WG:FZ [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho ARR:GISH [plasma membrane] (Drosophila melanogaster)
WG:FZ:Phospho (3 sites) ARR:GISH [plasma membrane] (Drosophila melanogaster)
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