Phosphorylation of CI by PKA-C1

Stable Identifier
R-DME-209196
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
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Cubitus Interruptus (CI) is primed for phosphorylation by Protein kinase A (PKA-C1) at Ser838, Ser856, and Ser892.

Literature References
PubMed ID Title Journal Year
10409506 Mutants of cubitus interruptus that are independent of PKA regulation are independent of hedgehog signaling

Chen, Y, Cardinaux, JR, Goodman, RH, Smolik, SM

Development 1999
10557210 Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus

Wang, G, Wang, B, Jiang, J

Genes Dev 1999
9482888 Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus

Chen, Y, Gallaher, N, Goodman, RH, Smolik, SM

Proc Natl Acad Sci U S A 1998
10477300 Proteolysis of cubitus interruptus in Drosophila requires phosphorylation by protein kinase A

Price, MA, Kalderon, D

Development 1999
Participants
Participates
Catalyst Activity

protein serine/threonine kinase activity of CNK:PHL:Phospho (2 sites) KSR:AVE:DSOR1:CK2:PAR-1:PP2A-29B:MTS [cytosol]

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