Upon arrival in the nucleus, truncated Cubitus Interruptus (CI75) represses transcription. Sensitive target genes include hh and dpp, but not ptc and repression depends on direct DNA-binding sites for CI75.
Methot, N, Basler, K
Kornberg, TB, Aza-Blanc, P, Schwartz, C, Ramirez-Weber, FA, Laget, MP
Basler, K, Müller, B
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