Phosphorylated REL-68 forms a complex with PCAF at its target gene and activates transcription

Stable Identifier
R-DME-209257
Type
Reaction [binding]
Species
Drosophila melanogaster
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In the nucleus, phosphorylated Relish (REL-68) forms a complex with the histone acetyltransferase, PCAF, at its target gene and transcription is activated.

Literature References
PubMed ID Title Journal Year
17803358 Down-regulation of NF-kappaB target genes by the AP-1 and STAT complex during the innate immune response in Drosophila

Kim, LK, Choi, UY, Cho, HS, Lee, JS, Lee, WB, Kim, J, Jeong, K, Shim, J, Kim-Ha, J, Kim, YJ

PLoS Biol 2007
15640802 Downregulation of lipopolysaccharide response in Drosophila by negative crosstalk between the AP1 and NF-kappaB signaling modules

Kim, T, Yoon, J, Cho, H, Lee, WB, Kim, J, Song, YH, Kim, SN, Yoon, JH, Kim-Ha, J, Kim, YJ

Nat Immunol 2005
10409696 Interaction and specificity of Rel-related proteins in regulating Drosophila immunity gene expression

Han, ZS, Ip, YT

J Biol Chem 1999
11269501 Activation of the Drosophila NF-kappaB factor Relish by rapid endoproteolytic cleavage

Stoven, S, Ando, I, Kadalayil, L, Engstrom, Y, Hultmark, D

EMBO Rep 2000
12732719 Caspase-mediated processing of the Drosophila NF-kappaB factor Relish

Stoven, S, Silverman, N, Junell, A, Hedengren-Olcott, M, Erturk, D, Engstrom, Y, Maniatis, T, Hultmark, D

Proc Natl Acad Sci U S A 2003
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