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aPKC [cell junction]
Stable Identifier
R-DME-2134483
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cell junction
Synonyms
PRKCZ, A1Z9X0
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by TGF-beta Receptor Complex (Drosophila melanogaster)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Drosophila melanogaster)
Disassembly of tight junctions (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
PARD3:p-PARD6A:PRKCZ [cell junction] (Drosophila melanogaster)
aPKC [cell junction] (Drosophila melanogaster)
SMURF1 binds phosphorylated PARD6A (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
PARD3:p-PARD6A:PRKCZ [cell junction] (Drosophila melanogaster)
aPKC [cell junction] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
PARD3:p-PARD6A:PRKCZ [cell junction] (Drosophila melanogaster)
aPKC [cell junction] (Drosophila melanogaster)
SMURF1 ubiquitinates RHOA (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
PARD3:p-PARD6A:PRKCZ [cell junction] (Drosophila melanogaster)
aPKC [cell junction] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Drosophila melanogaster)
Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Drosophila melanogaster)
PARD3:p-PARD6A:PRKCZ [cell junction] (Drosophila melanogaster)
aPKC [cell junction] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:A1Z9X0
Gene Names
aPKC
Reference Genes
BioGPS Gene:47594 aPKC
CTD Gene:47594 aPKC
ENSEMBL:FBgn0261854
FlyBase:FBgn0261854
KEGG:dme:Dmel_CG42783 aPKC
Monarch:47594 aPKC
NCBI Gene:47594 aPKC
UCSC:A1Z9X0 aPKC
Reference Transcript
RefSeq:NM_001043078.2 aPKC
RefSeq:NM_001043080.3 aPKC
RefSeq:NM_080153.5 aPKC
RefSeq:NM_001043079.2 aPKC
RefSeq:NM_001043076.3 aPKC
RefSeq:NM_001043077.3 aPKC
Other Identifiers
147229_at
1627948_at
1640307_at
47594
GO:0000132
GO:0000166
GO:0001738
GO:0002052
GO:0002376
GO:0003382
GO:0003824
GO:0004672
GO:0004674
GO:0004697
GO:0005515
GO:0005524
GO:0005737
GO:0005886
GO:0005938
GO:0006468
GO:0007010
GO:0007043
GO:0007163
GO:0007283
GO:0007294
GO:0007314
GO:0007416
GO:0007423
GO:0007430
GO:0007613
GO:0008270
GO:0010592
GO:0012501
GO:0016020
GO:0016301
GO:0016324
GO:0016327
GO:0016332
GO:0016334
GO:0016740
GO:0017022
GO:0022414
GO:0030010
GO:0030011
GO:0030154
GO:0030165
GO:0030860
GO:0034330
GO:0034332
GO:0035003
GO:0035011
GO:0035331
GO:0035556
GO:0043296
GO:0045087
GO:0045167
GO:0045176
GO:0045179
GO:0045186
GO:0045196
GO:0045197
GO:0045198
GO:0045880
GO:0046667
GO:0046872
GO:0048856
GO:0050877
GO:0051491
GO:0051601
GO:0055059
GO:0060446
GO:0072659
GO:0090163
GO:0098542
GO:0106310
GO:0120157
GO:0140096
GO:0140591
GO:1904580
Participates
as a component of
PARD3:p-PARD6A:PRKCZ [cell junction] (Drosophila melanogaster)
Other forms of this molecule
phospho-aPKC [cytosol]
aPKC [cytosol]
phospho-aPKC [cytosol]
phospho-aPKC [cytosol]
aPKC [cytosol]
Inferred From
PRKCZ [cell junction]
(Homo sapiens)
Cross References
RefSeq
NP_524892.2
,
NP_001036541.1
,
NP_001036543.1
,
NP_001036542.1
,
NP_001036545.1
,
NP_001036544.1
ENSEMBL
FBpp0292491
,
FBtr0303434
,
FBpp0292487
,
FBgn0261854
,
FBtr0303430
IntEnz
2.7.11.13
FlyBase
FBgn0261854
PRO
A1Z9X0
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O97111
4
par-6 [cytosol]
(R-DME-419967)
par-6 [cytosol]
(R-DME-419973)
par-6 [cytosol]
(R-DME-420001)
phospho-par-6 [plasma membrane]
(R-DME-2134533)
0.753
7
UniProt:O96782 O96782
0.637
3
UniProt:Q9VX75 Q9VX75
0.571
3
UniProt:P08111 L2GL
0.564
2
UniProt:P10040
7
crb [Golgi membrane]
(R-DME-157073)
crb [Golgi membrane]
(R-DME-1983674)
crb [extracellular region]
(R-DME-1983677)
crb [plasma membrane]
(R-DME-157213)
crb [cytosol]
(R-DME-157636)
phospho-crb [cytosol]
(R-DME-9604329)
crb [nucleoplasm]
(R-DME-157945)
0.544
3
UniProt:Q9NB04
1
Patj [cytosol]
(R-DME-8851641-3)
0.544
2
UniProt:P16554 NUMB
0.525
4
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