Reactome | KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]

KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane]

Stable Identifier

R-DME-265734

Type

Complex

Species

Drosophila melanogaster

Compartment

plasma membrane

Locations in the PathwayBrowser

Expand all

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 4 ABCC8:Mg2+:ADP [plasma membrane] (Drosophila melanogaster)
x 4 Homologues of KCNJ11 [plasma membrane] (Drosophila melanogaster)

Participates

as an input of

Meglitinides bind ABCC8 (Drosophila melanogaster)
SU drugs bind ABCC8 (in KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer) (Drosophila melanogaster)
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Drosophila melanogaster)

as a component of

ABCC8:Meglitinides [plasma membrane] (Drosophila melanogaster)
ABCC8:SU drugs [plasma membrane] (Drosophila melanogaster)

Inferred From

KCNJ11 tetramer:ABCC8:Mg2+:ADP tetramer [plasma membrane] (Homo sapiens)

Cite Us!