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EPHB4 [plasma membrane]
Stable Identifier
R-DME-2682323
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
Q9V4E5
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
EPH receptors autophosphorylate (Drosophila melanogaster)
EPH-ephrin oligomers [plasma membrane] (Drosophila melanogaster)
EPHB:EFNB oligomers [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPH-ephrin mediated repulsion of cells (Drosophila melanogaster)
Clathrin internalises EPH:EFN complexes (Drosophila melanogaster)
EPHB:EFNB:F-actin:AP-2:Clathrrin:Dynamin [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
MMP2,9 cleave EPHB (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPH:EFN dimers tetramerise (Drosophila melanogaster)
EPH-EFN dimers [plasma membrane] (Drosophila melanogaster)
EPHB:EFNB dimers [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPH:EFN tetramers oligomerise (Drosophila melanogaster)
EPH-EFN dimers [plasma membrane] (Drosophila melanogaster)
EPHB:EFNB dimers [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPH-ephrin oligomers [plasma membrane] (Drosophila melanogaster)
EPHB:EFNB oligomers [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHBs bind EFNBs (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
Ephrin signaling (Drosophila melanogaster)
EFNB:GRB4 binds GIT1 (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EFNBs bind SDCBP (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs:SDCBP [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EFNBs bind SFKs (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
GIT1 binds bPIX (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
PAK binds RAC and bPIX (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
PAKs autophosphorylate (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
PAKs phosphorylate MLC (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
bPIX exchanges GTP for GDP on RAC, activating it (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
p-EFNB binds GRB4 (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4 [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs:SRC,FYN [plasma membrane] (Drosophila melanogaster)
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHB4 [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9V4E5
Reference Genes
BioGPS Gene:43803 Q0KIF4
ENSEMBL:FBgn0025936
FlyBase:FBgn0025936
Monarch:43803 Q0KIF4
NCBI Gene:43803 Q0KIF4
UCSC:Q9V4E5
Reference Transcript
RefSeq:NM_079886.5
Other Identifiers
144106_at
1641458_s_at
43803
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005003
GO:0005005
GO:0005515
GO:0005524
GO:0005886
GO:0006468
GO:0007169
GO:0007411
GO:0007422
GO:0009653
GO:0016020
GO:0016319
GO:0016740
GO:0022008
GO:0030154
GO:0033674
GO:0035011
GO:0038127
GO:0043005
GO:0043235
GO:0046777
GO:0048013
GO:0048513
GO:0048856
GO:0060089
GO:0098542
GO:0140096
Participates
as a component of
EPHBs:p-3Y-EFNBs [plasma membrane] (Drosophila melanogaster)
EPHBs:EFNBs [plasma membrane] (Drosophila melanogaster)
as an input of
EPHBs bind EFNBs (Drosophila melanogaster)
Other forms of this molecule
EPHA2 [plasma membrane]
Q9V4E5 [plasma membrane]
EPHB4 (?-987) [cytosol]
EPHB4 (?-987) [plasma membrane]
EPHB4 (16-?) [extracellular region]
EPHA1 [plasma membrane]
phospho-p-Y590,Y596-EPHB4 [plasma membrane]
phospho-Q9V4E5 [plasma membrane]
phospho-p-Y588,Y594-EPHA2 [plasma membrane]
Inferred From
EPHBs [plasma membrane]
(Homo sapiens)
EPHB4 [plasma membrane]
(Homo sapiens)
Cross References
ENSEMBL
FBgn0025936
,
FBtr0089084
,
FBpp0088153
FlyBase
FBgn0025936
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