Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
ITPR1 [endoplasmic reticulum membrane]
Stable Identifier
R-DME-3006433
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
endoplasmic reticulum membrane
Synonyms
P29993
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Signaling by the B Cell Receptor (BCR) (Drosophila melanogaster)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Drosophila melanogaster)
STIM1 oligomerizes (Drosophila melanogaster)
ITPR:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane] (Drosophila melanogaster)
Ca-channel (closed) [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR1 tetramer [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR1 [endoplasmic reticulum membrane] (Drosophila melanogaster)
Metabolism (Drosophila melanogaster)
Integration of energy metabolism (Drosophila melanogaster)
Regulation of insulin secretion (Drosophila melanogaster)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Drosophila melanogaster)
ER calcium channels open in response to activated PKA (Drosophila melanogaster)
Ca-channel (closed) [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR1 tetramer [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR1 [endoplasmic reticulum membrane] (Drosophila melanogaster)
Ca-channel (open) [endoplasmic reticulum membrane] (Drosophila melanogaster)
IP3-gated Ca-channel type 1 (open) [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR1 [endoplasmic reticulum membrane] (Drosophila melanogaster)
Muscle contraction (Drosophila melanogaster)
Cardiac conduction (Drosophila melanogaster)
Ion homeostasis (Drosophila melanogaster)
AHCYL1:NAD+ binds ITPR1:I(1,3,5)P3 tetramer, inhibiting it (Drosophila melanogaster)
AHCYL1:NAD+:ITPR1:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane] (Drosophila melanogaster)
Ca-channel (closed) [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR1 tetramer [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR1 [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR:I(1,4,5)P3 tetramer [endoplasmic reticulum membrane] (Drosophila melanogaster)
Ca-channel (closed) [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR1 tetramer [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR1 [endoplasmic reticulum membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P29993
Reference Genes
BioGPS Gene:40664
CTD Gene:40664
ENSEMBL:FBgn0010051
Flybase:FBgn0010051
KEGG Gene (Drosophila melanogaster):Dmel_CG1063
Monarch:40664
NCBI Gene:40664
Reference Transcript
RefSeq:NM_169060.2
RefSeq:NM_001300251.1
RefSeq:NM_169061.2
Other Identifiers
143580_at
1639461_a_at
40664
GO:0005215
GO:0005216
GO:0005220
GO:0005262
GO:0005783
GO:0006811
GO:0006816
GO:0016020
GO:0023052
GO:0043226
GO:0055085
GO:0070588
GO:0070679
Participates
as a component of
IP3-gated Ca-channel type 1 (open) [endoplasmic reticulum membrane] (Drosophila melanogaster)
ITPR1 tetramer [endoplasmic reticulum membrane] (Drosophila melanogaster)
Other forms of this molecule
ITPR2 [platelet dense tubular network membrane]
ITPR3 [platelet dense tubular network membrane]
ITPR1 [platelet dense tubular network membrane]
ITPR2 [endoplasmic reticulum membrane]
ITPR3 [endoplasmic reticulum membrane]
Inferred From
ITPR1 [endoplasmic reticulum membrane]
(Homo sapiens)
Cross References
RefSeq
NP_730942.1
,
NP_001287180.1
,
NP_730941.1
Flybase
FBgn0010051
PRO
P29993
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text