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MBD-R2 [nucleoplasm]
Stable Identifier
R-DME-3222239
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
PHF20, Q9VGA4
Locations in the PathwayBrowser
Expand all
Chromatin organization (Drosophila melanogaster)
Chromatin modifying enzymes (Drosophila melanogaster)
HATs acetylate histones (Drosophila melanogaster)
NSL acetylates histone H4 (Drosophila melanogaster)
NSL (PHF20) [nucleoplasm] (Drosophila melanogaster)
MBD-R2 [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
Epigenetic regulation of gene expression (Drosophila melanogaster)
Formation of WDR5-containing histone-modifying complexes (Drosophila melanogaster)
Formation of the NSL complex (Drosophila melanogaster)
MBD-R2 [nucleoplasm] (Drosophila melanogaster)
NSL [nucleoplasm] (Drosophila melanogaster)
NSL (PHF20) [nucleoplasm] (Drosophila melanogaster)
MBD-R2 [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
Regulation of TP53 Activity (Drosophila melanogaster)
Regulation of TP53 Activity through Association with Co-factors (Drosophila melanogaster)
AKT phosphorylates PHF20 (Drosophila melanogaster)
MBD-R2 [nucleoplasm] (Drosophila melanogaster)
PHF20 binds TP53 dimethylated on K370 and K382 (Drosophila melanogaster)
MBD-R2 [nucleoplasm] (Drosophila melanogaster)
PHF20:Me2-K370,K382-TP53 Tetramer [nucleoplasm] (Drosophila melanogaster)
MBD-R2 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VGA4
Gene Names
MBD-R2
Reference Genes
BioGPS Gene:41498 MBD-R2
ENSEMBL:FBgn0038016
Flybase:FBgn0038016
KEGG Gene (Drosophila melanogaster):Dmel_CG10042 MBD-R2
Monarch:41498 MBD-R2
NCBI Gene:41498 MBD-R2
UCSC:Q9VGA4 MBD-R2
Reference Transcript
RefSeq:NM_169461.3 MBD-R2
Other Identifiers
149751_s_at
1638609_s_at
41498
GO:0000785
GO:0000791
GO:0003677
GO:0003824
GO:0005515
GO:0005634
GO:0005694
GO:0005700
GO:0005705
GO:0006351
GO:0006355
GO:0006357
GO:0016573
GO:0016787
GO:0036211
GO:0043226
GO:0044545
GO:0045944
GO:0046872
GO:1990841
Participates
as an input of
Formation of the NSL complex (Drosophila melanogaster)
AKT phosphorylates PHF20 (Drosophila melanogaster)
PHF20 binds TP53 dimethylated on K370 and K382 (Drosophila melanogaster)
as a component of
NSL (PHF20) [nucleoplasm] (Drosophila melanogaster)
PHF20:Me2-K370,K382-TP53 Tetramer [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
MBD-R2 [nucleoplasm]
phospho-MBD-R2 [nucleoplasm]
Inferred From
PHF20, PHF20L1 [nucleoplasm]
(Homo sapiens)
PHF20 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_731688.2
Flybase
FBgn0038016
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:A4V2Z1 A4V2Z1
0.499
5
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