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hyx [nucleoplasm]
Stable Identifier
R-DME-3322360
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
CDC73, Q9VHI1
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
RNA Polymerase II Pre-transcription Events (Drosophila melanogaster)
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Drosophila melanogaster)
Paused processive elongation complex [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Abortive termination of elongation after arrest (Drosophila melanogaster)
Aborted elongation complex after arrest [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Resumption of elongation after recovery from pausing (Drosophila melanogaster)
Paused processive elongation complex [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
TFIIS-mediated recovery of elongation from arrest (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription Elongation (Drosophila melanogaster)
Addition of nucleotides leads to transcript elongation (Drosophila melanogaster)
Elongation complex [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Formation of RNA Pol II elongation complex (Drosophila melanogaster)
Recruitment of elongation factors to form elongation complex (Drosophila melanogaster)
Elongation complex [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Pol II elongation complex moves on the template as transcript elongates (Drosophila melanogaster)
Elongation complex prior to separation [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Processive elongation complex [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Separation of elongating transcript from template (Drosophila melanogaster)
Elongation complex prior to separation [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Protein ubiquitination (Drosophila melanogaster)
E3 ubiquitin ligases ubiquitinate target proteins (Drosophila melanogaster)
RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
PAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2B [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
RNF20:RNF40 monoubiquitinates Histone H2B (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
PAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2B [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Hedgehog (Drosophila melanogaster)
Hedgehog 'on' state (Drosophila melanogaster)
GLI proteins bind CDC73 (Drosophila melanogaster)
CDC73:2p-GLI [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
TCF dependent signaling in response to WNT (Drosophila melanogaster)
Formation of the beta-catenin:TCF transactivating complex (Drosophila melanogaster)
Beta-catenin recruits CDC73 and LEO1 (Drosophila melanogaster)
TCF/LEF:CTNNB1:PAF1-like complex [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
hyx [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VHI1
Gene Names
hyx
Reference Genes
BioGPS Gene:41086 hyx
CTD Gene:41086 hyx
ENSEMBL:FBgn0037657
Flybase:FBgn0037657
KEGG Gene (Drosophila melanogaster):Dmel_CG11990 hyx
Monarch:41086 hyx
NCBI Gene:41086 hyx
UCSC:Q9VHI1 hyx
Reference Transcript
RefSeq:NM_141606.4 hyx
RefSeq:NM_001170093.2 hyx
Other Identifiers
141288_at
1634550_at
41086
GO:0000993
GO:0001745
GO:0005634
GO:0005654
GO:0005667
GO:0006351
GO:0006355
GO:0006368
GO:0007480
GO:0008134
GO:0008407
GO:0008586
GO:0008587
GO:0016071
GO:0016570
GO:0016593
GO:0023052
GO:0032968
GO:0034402
GO:0036211
GO:0043226
GO:0045880
GO:0045944
GO:0048856
GO:0065003
GO:0090263
Participates
as an input of
GLI proteins bind CDC73 (Drosophila melanogaster)
Beta-catenin recruits CDC73 and LEO1 (Drosophila melanogaster)
as a component of
CDC73:2p-GLI [nucleoplasm] (Drosophila melanogaster)
PAF1C [nucleoplasm] (Drosophila melanogaster)
TCF/LEF:CTNNB1:PAF1-like complex [nucleoplasm] (Drosophila melanogaster)
Inferred From
CDC73 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_649863.1
,
NP_001163564.1
Flybase
FBgn0037657
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