Reactome | Spn77Ba [extracellular region]

Spn77Ba [extracellular region]

Stable Identifier

R-DME-374187

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

extracellular region

Synonyms

AGT(34-41), Q0E8C8

Locations in the PathwayBrowser

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Signal Transduction (Drosophila melanogaster)

- Signaling by GPCR (Drosophila melanogaster)
  - GPCR downstream signalling (Drosophila melanogaster)
    - G alpha (i) signalling events (Drosophila melanogaster)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
        
        AGTR2:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
        
        AGTR2:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
        
        AGTR2:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
        
        AGTR2:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
      - The Ligand:GPCR:Gi complex dissociates (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
        
        AGTR2:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Drosophila melanogaster)
        
        AGTR2:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
    - G alpha (q) signalling events (Drosophila melanogaster)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        AGTR1:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        AGTR1:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        AGTR1:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        AGTR1:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
      - The Ligand:GPCR:Gq complex dissociates (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        AGTR1:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
        
        Ligands of GPCRs that activate Gq/11 [extracellular region] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
  - GPCR ligand binding (Drosophila melanogaster)
    - Class A/1 (Rhodopsin-like receptors) (Drosophila melanogaster)
      - Peptide ligand-binding receptors (Drosophila melanogaster)
        
        AGT(34-41) binds to AGTR1 (Drosophila melanogaster)
        
        AGTR1:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
        
        AGT(34-41) binds to AGTR2 (Drosophila melanogaster)
        
        AGTR2:AGT(34-41) [plasma membrane] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)
        
        Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)
        
        Spn77Ba [extracellular region] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q0E8C8

Gene Names

Spn77Ba

Reference Genes

BioGPS Gene:40234 Spn77Ba

ENSEMBL:FBgn0262057

Flybase:FBgn0262057

KEGG Gene (Drosophila melanogaster):Dmel_CG6680 Spn77Ba

Monarch:40234 Spn77Ba

NCBI Gene:40234 Spn77Ba

UCSC:Q0E8C8 Spn77Ba

Reference Transcript

Other Identifiers

153042_at

1631179_s_at

40234

GO:0002376

GO:0003674

GO:0004867

GO:0005575

GO:0005576

GO:0005615

GO:0006950

GO:0008150

GO:0009058

GO:0010466

GO:0010951

GO:0019748

GO:0030234

GO:0030414

GO:0035009

GO:0042438

GO:0045861

Participates

as a member of

Homologues of AGT(34-41) [extracellular region] (Drosophila melanogaster)

Other forms of this molecule

Spn77Ba [cytosol]

Spn77Ba [extracellular region]

Spn77Ba [endoplasmic reticulum lumen]

Spn77Ba [lysosomal lumen]

Spn77Ba [secretory granule membrane]

Spn77Ba [plasma membrane]

Spn77Ba [ficolin-1-rich granule membrane]

Spn77Ba [plasma membrane]

Spn77Ba [tertiary granule membrane]

Spn77Ba [extracellular region]

Spn77Ba [azurophil granule lumen]

phospho-Spn77Ba [endoplasmic reticulum lumen]

Spn77Ba [endoplasmic reticulum lumen]

Spn77Ba [extracellular region]

Inferred From

AGT(34-41) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_730512.2, NP_649205.3, NP_001287128.1

Flybase

FBgn0262057

PRO

Q0E8C8

GlyGen

Q0E8C8

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