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SIAH2 [cytosol]
Stable Identifier
R-DME-374566-2
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q8T3Y0
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
Netrin-1 signaling (Drosophila melanogaster)
DCC interaction with SIAH2 (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
NTN1:DCC:SIAH2 [plasma membrane] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Class I MHC mediated antigen processing & presentation (Drosophila melanogaster)
Antigen processing: Ubiquitination & Proteasome degradation (Drosophila melanogaster)
Interaction of E3 with substrate and E2-Ub complex (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
Polyubiquitination of substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
Release of E3 from polyubiquitinated substrate (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
E3:K48-polyubiquitinated substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
Transfer of Ub from E2 to substrate and release of E2 (Drosophila melanogaster)
Ag-substrate:E3:E2:Ub [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
E3:Ub:substrate [cytosol] (Drosophila melanogaster)
E3 ligases in proteasomal degradation [cytosol] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Deubiquitination (Drosophila melanogaster)
Ub-specific processing proteases (Drosophila melanogaster)
USP13 binds SIAH2 (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2:USP13 [cytosol] (Drosophila melanogaster)
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
SIAH2 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q8T3Y0
Reference Genes
BioGPS Gene:39885
CTD Gene:39885
ENSEMBL:FBgn0259794
Flybase:FBgn0259794
KEGG Gene (Drosophila melanogaster):Dmel_CG13030
Monarch:39885
NCBI Gene:39885
UCSC:Q8T3Y0
Reference Transcript
RefSeq:NM_140670.2
Other Identifiers
148919_at
1638838_at
39885
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005737
GO:0006511
GO:0007275
GO:0007423
GO:0008270
GO:0010498
GO:0016567
GO:0016740
GO:0030154
GO:0030163
GO:0031624
GO:0036211
GO:0043161
GO:0043226
GO:0045676
GO:0046872
GO:0048856
GO:0061630
GO:0140096
Participates
as a member of
Homologues of SIAH2 [cytosol] (Drosophila melanogaster)
Inferred From
SIAH2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_648927.1
Flybase
FBgn0259794
IntEnz
2.3.2.27
PRO
Q8T3Y0
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VBQ3
1
Dmel\CG5111 [cytosol]
(R-DME-8956129)
0.621
3
UniProt:O62602
6
lic [cytosol]
(R-DME-167998)
lic [cytosol]
(R-DME-168051)
phospho-lic [cytosol]
(R-DME-206255)
phospho-lic [cytosol]
(R-DME-167955)
phospho-lic [nucleoplasm]
(R-DME-450258)
phospho-lic [nucleoplasm]
(R-DME-450229)
0.488
2
UniProt:P25867 eff
4
EFF [cytosol]
(R-DME-205773)
eff [cytosol]
(R-DME-8864160)
eff [nucleoplasm]
(R-DME-174197)
eff [cytosol]
(R-DME-174236)
0.488
2
UniProt:Q9W420
1
Spt6 [nucleoplasm]
(R-DME-8932908)
0.488
2
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