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Syb [plasma membrane]
Stable Identifier
R-DME-376365-2
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
VAMP8, P18489
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Neutrophil degranulation (Drosophila melanogaster)
Exocytosis of azurophil granule membrane proteins (Drosophila melanogaster)
Azurophil granule membrane proteins [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
Exocytosis of specific granule membrane proteins (Drosophila melanogaster)
Specific granule membrane proteins [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
Exocytosis of tertiary granule membrane proteins (Drosophila melanogaster)
Tertiary granule membrane proteins [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Clathrin-mediated endocytosis (Drosophila melanogaster)
BAR domain proteins recruit dynamin (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
Cargo recognition for clathrin-mediated endocytosis (Drosophila melanogaster)
PICALM binds R-SNAREs (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
Clathrin recruits PIK3C2A (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
Endophilins recruit synaptojanins to the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
F- and N- BAR domain proteins bind the clathrin-coated pit (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Drosophila melanogaster)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Drosophila melanogaster)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
CLASP proteins:cargo [plasma membrane] (Drosophila melanogaster)
PICALM:VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
VAMP2,3,8 [plasma membrane] (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
trans-Golgi Network Vesicle Budding (Drosophila melanogaster)
Vamp8 associated secretory vesicle to plasma membrane transport (Drosophila melanogaster)
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Syb [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P18489
Gene Names
Syb
Reference Genes
BioGPS Gene:36080 Syb
ENSEMBL:FBgn0003660
Flybase:FBgn0003660
KEGG Gene (Drosophila melanogaster):Dmel_CG12210 Syb
Monarch:36080 Syb
NCBI Gene:36080 Syb
Reference Transcript
RefSeq:NM_001144162.2 Syb
RefSeq:NM_001299349.1 Syb
RefSeq:NM_001144161.2 Syb
RefSeq:NM_078956.4 Syb
RefSeq:NM_165756.3 Syb
Other Identifiers
141625_at
1635944_a_at
1637089_at
36080
GO:0000149
GO:0005484
GO:0005886
GO:0006906
GO:0007269
GO:0008021
GO:0016020
GO:0016081
GO:0016192
GO:0019905
GO:0023052
GO:0030672
GO:0031201
GO:0031340
GO:0031410
GO:0043226
GO:0045202
GO:0060090
GO:0061024
Participates
as a member of
Homologues of VAMP8 [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
Syb [clathrin-coated endocytic vesicle membrane]
Syb [clathrin-coated endocytic vesicle membrane]
Syb [secretory granule membrane]
Syb [cytoplasmic vesicle membrane]
Syb [Golgi membrane]
Syb [Golgi membrane]
Syb [lysosomal membrane]
Syb [lysosomal membrane]
Syb [cytoplasmic vesicle membrane]
Syb [cytosol]
Syb [secretory granule membrane]
Syb [azurophil granule membrane]
Syb [specific granule membrane]
Syb [tertiary granule membrane]
Syb [clathrin-sculpted glutamate transport vesicle membrane]
Syb [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
Syb [plasma membrane]
Syb [clathrin-sculpted monoamine transport vesicle membrane]
Inferred From
VAMP8 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001286278.1
,
NP_001137633.1
,
NP_001137634.1
,
NP_724906.1
,
NP_523680.1
Flybase
FBgn0003660
PRO
P18489
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q24547
7
Syx1A [cytosol]
(R-DME-9609866)
phospho-Syx1A [cytosol]
(R-DME-114681)
Syx1A [cytosol]
(R-DME-114505)
Syx1A [phagocytic vesicle membrane]
(R-DME-2029044)
Syx1A [plasma membrane]
(R-DME-181519)
Syx1A [plasma membrane]
(R-DME-449131)
Syx1A [plasma membrane]
(R-DME-449128)
0.636
4
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