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phospho-p-S141,T402-PAK2 [cytosol]
Stable Identifier
R-DME-399824-2
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q9VI13
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
Semaphorin interactions (Drosophila melanogaster)
Sema3A PAK dependent Axon repulsion (Drosophila melanogaster)
Autophosphorylation of PAK (Drosophila melanogaster)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Drosophila melanogaster)
p-S,T-PAK1,2,3 [cytosol] (Drosophila melanogaster)
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
phospho-p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
Phosphorylation of LIMK-1 by PAK (Drosophila melanogaster)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:pPAK [plasma membrane] (Drosophila melanogaster)
p-S,T-PAK1,2,3 [cytosol] (Drosophila melanogaster)
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
phospho-p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
p-S,T-PAK1,2,3 [cytosol] (Drosophila melanogaster)
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
phospho-p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
FCERI mediated MAPK activation (Drosophila melanogaster)
Autophosphorylation of PAK (Drosophila melanogaster)
p-2Y-PAK [cytosol] (Drosophila melanogaster)
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
phospho-p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK6/MAPK4 signaling (Drosophila melanogaster)
Autophosphorylation of PAK1,2,3 (Drosophila melanogaster)
p-S,T-PAK1,2,3 [cytosol] (Drosophila melanogaster)
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
phospho-p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
FYN phosphorylates PAK2 (Drosophila melanogaster)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p-2Y-PAK2 dimer [cytosol] (Drosophila melanogaster)
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
phospho-p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
PAK2 autophorylates (Drosophila melanogaster)
VEGFA:p-6Y-VEGFR2:NCK:p-S21,Y420-FYN:p-2Y-PAK2:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p-2Y-PAK2 dimer:CDC42:GTP [plasma membrane] (Drosophila melanogaster)
p-2Y-PAK2 dimer [cytosol] (Drosophila melanogaster)
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
phospho-p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
PAK1-3 autophosphorylates (Drosophila melanogaster)
p-S,T-PAK1,2,3 [cytosol] (Drosophila melanogaster)
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
phospho-p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
PAK1-3 phosphorylates VE-cadherin (Drosophila melanogaster)
p-S,T-PAK1,2,3 [cytosol] (Drosophila melanogaster)
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
phospho-p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases activate PAKs (Drosophila melanogaster)
Autophosphorylation of PAK1,2,3 (Drosophila melanogaster)
p-S,T-PAK1,2,3 [cytosol] (Drosophila melanogaster)
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
phospho-p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Drosophila melanogaster)
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
phospho-p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VI13 Pak
Gene Names
Pak, DPAK, Dpak1, CG10295
Chain
chain:1-704
Reference Genes
BioGPS Gene:44039 Pak
CTD Gene:44039 Pak
KEGG Gene (Drosophila melanogaster):Dmel_CG10295 Pak
Monarch:44039 Pak
NCBI Gene:44039 Pak
UCSC:Q9VI13 Pak
Reference Transcript
RefSeq:NM_001275380.2 Pak
RefSeq:NM_079942.4 Pak
RefSeq:NM_169137.3 Pak
RefSeq:NM_001275384.1 Pak
RefSeq:NM_169136.3 Pak
Other Identifiers
153976_at
1634405_s_at
44039
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005737
GO:0005829
GO:0005856
GO:0005884
GO:0005886
GO:0005925
GO:0006468
GO:0007155
GO:0007391
GO:0007395
GO:0007411
GO:0007480
GO:0012501
GO:0016301
GO:0016310
GO:0016328
GO:0016740
GO:0017124
GO:0019991
GO:0023052
GO:0030154
GO:0031252
GO:0031267
GO:0031594
GO:0034330
GO:0035072
GO:0035556
GO:0036211
GO:0043067
GO:0043226
GO:0043408
GO:0045887
GO:0048856
GO:0048870
GO:0050770
GO:0050803
GO:0070161
GO:0090128
GO:0097482
GO:0098696
GO:0140096
Participates
as a member of
Homologues of p-S141,T402-PAK2 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
PAK1 [plasma membrane]
phospho-p-S154,T436-PAK3 [plasma membrane]
phospho-p-S144,T423-PAK1 [plasma membrane]
phospho-p-S141,T402-PAK2 [plasma membrane]
Pak [cytosol]
phospho-p-Y130,S141,T402-PAK2 [cytosol]
phospho-p-S154,T436-PAK3 [cytosol]
PAK3 [cytosol]
PAK1 [cytosol]
PAK2 [cytosol]
phospho-p-S144,T423-PAK1 [cytosol]
Inferred From
p-S141,T402-PAK2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 141 (in Homo sapiens)
Coordinate
141
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 402 (in Homo sapiens)
Coordinate
402
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_524681.1
,
NP_001262309.1
,
NP_731073.1
,
NP_731074.1
,
NP_001262313.1
Flybase
FBgn0267698
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P40792 Rac1
12
RAC2 [mitochondrial outer membrane]
(R-DME-9714496)
RAC2 [phagocytic vesicle membrane]
(R-DME-5668620)
RAC1 [ficolin-1-rich granule membrane]
(R-DME-6804802)
RAC1 [secretory granule membrane]
(R-DME-6804770)
RHOG [secretory granule membrane]
(R-DME-6804965)
GGC-PalmC-RAC1 [plasma membrane]
(R-DME-2316446)
RAC1 [endoplasmic reticulum membrane]
(R-DME-5672076)
RHOG [endoplasmic reticulum membrane]
(R-DME-5672084)
RHOG [cytosol]
(R-DME-194909)
RAC1_DROME [cytosol]
(R-DME-428467)
RHOG [plasma membrane]
(R-DME-194880)
RAC1 [plasma membrane]
(R-DME-351103)
0.766
5
UniProt:Q8IPW2 dock
1
DOCK [cytosol]
(R-DME-179477)
0.635
3
UniProt:P48554
9
RAC2 [endoplasmic reticulum membrane]
(R-DME-9714482)
RAC2 [mitochondrial outer membrane]
(R-DME-9714496-2)
RAC2 [phagocytic vesicle membrane]
(R-DME-5668620-2)
RHOG [secretory granule membrane]
(R-DME-6804965-2)
RHOG [endoplasmic reticulum membrane]
(R-DME-5672084-2)
RHOG [cytosol]
(R-DME-194909-2)
RAC2 [cytosol]
(R-DME-195343)
RHOG [plasma membrane]
(R-DME-194880-2)
RAC2 [plasma membrane]
(R-DME-195339)
0.632
3
UniProt:O44924 robo
1
Robo1_DROME [plasma membrane]
(R-DME-428452)
0.482
5
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