Reactome | AstA-R2 [plasma membrane]

AstA-R2 [plasma membrane]

Stable Identifier

R-DME-416410-2

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

plasma membrane

Synonyms

LTB4R, Q9NBC8

Locations in the PathwayBrowser

Expand all

Signal Transduction (Drosophila melanogaster)

- Signaling by GPCR (Drosophila melanogaster)
  - GPCR downstream signalling (Drosophila melanogaster)
    - G alpha (q) signalling events (Drosophila melanogaster)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of LTB4R [plasma membrane] (Drosophila melanogaster)
        
        AstA-R2 [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of LTB4R [plasma membrane] (Drosophila melanogaster)
        
        AstA-R2 [plasma membrane] (Drosophila melanogaster)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of LTB4R [plasma membrane] (Drosophila melanogaster)
        
        AstA-R2 [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of LTB4R [plasma membrane] (Drosophila melanogaster)
        
        AstA-R2 [plasma membrane] (Drosophila melanogaster)
      - The Ligand:GPCR:Gq complex dissociates (Drosophila melanogaster)
        
        GPCRs that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of LTB4R [plasma membrane] (Drosophila melanogaster)
        
        AstA-R2 [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of LTB4R [plasma membrane] (Drosophila melanogaster)
        
        AstA-R2 [plasma membrane] (Drosophila melanogaster)
  - GPCR ligand binding (Drosophila melanogaster)
    - Class A/1 (Rhodopsin-like receptors) (Drosophila melanogaster)
      - Eicosanoid ligand-binding receptors (Drosophila melanogaster)
        
        Leukotriene receptors (Drosophila melanogaster)
        
        BLT receptors can bind LTB4 (Drosophila melanogaster)
        
        LTB4R,LTB4R2 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of LTB4R [plasma membrane] (Drosophila melanogaster)
        
        AstA-R2 [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2:LTB [plasma membrane] (Drosophila melanogaster)
        
        LTB4R,LTB4R2 [plasma membrane] (Drosophila melanogaster)
        
        Homologues of LTB4R [plasma membrane] (Drosophila melanogaster)
        
        AstA-R2 [plasma membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9NBC8

Gene Names

AstA-R2

Reference Genes

BioGPS Gene:43393 AstA-R2

ENSEMBL:FBgn0039595

FlyBase:FBgn0039595

Monarch:43393 AstA-R2

NCBI Gene:43393 AstA-R2

UCSC:Q9NBC8 AstA-R2

Reference Transcript

Other Identifiers

150781_at

1634874_at

43393

GO:0004930

GO:0004983

GO:0005886

GO:0007165

GO:0007186

GO:0007218

GO:0008188

GO:0008261

GO:0008528

GO:0016020

GO:0023052

GO:0060089

Participates

as a member of

Homologues of LTB4R [plasma membrane] (Drosophila melanogaster)

Other forms of this molecule

AstA-R2 [specific granule membrane]

AstA-R2 [tertiary granule membrane]

AstA-R2 [plasma membrane]

Inferred From

LTB4R [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_524544.1, NP_001263042.1

Flybase

FBgn0039595