Activation of Rac by Sos

Stable Identifier
R-DME-428523
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
cytosol, plasma membrane
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Activation of Rac by Sos
In Drosophila, Sos bound to Dock has a Rac GEF activity and activates Rac1 (Yang and Bashaw 2006).
Literature References
Participants
Input
Output
Catalyst Activity

guanyl-nucleotide exchange factor activity of Sos:PAK:Dock:Robo:Slit [plasma membrane]

Physical Entity
Sos:PAK:Dock:Robo:Slit [plasma membrane] (Drosophila melanogaster)
Activity
guanyl-nucleotide exchange factor activity (GO:0005085)
Orthologous Events
Activation of RAC1 by SOS (Homo sapiens)
Authored
Garapati, P V  (2008-09-05)
Reviewed
Jaworski, A  (2017-07-31)
Kidd, T  (2009-08-18)
Created
Garapati, P V  (2009-07-06)
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