TIM is phosphorylated by CK2

Stable Identifier
R-DME-432535
Type
Reaction [transition]
Species
Drosophila melanogaster
Compartment
ReviewStatus
5/5
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Timeless (TIM) is phosphorylated on unknown serine/threonine residues by casein kinase II (CK2). CK2 phosphorylation appears to be important for subsequent nuclear entry of TIM.
Literature References
PubMed ID Title Journal Year
18815259 TIMELESS is an important mediator of CK2 effects on circadian clock function in vivo

Kilman, VL, Allada, R, Lin, JM, Meissner, RA

J Neurosci 2008
Participants
Participates
Catalyst Activity

protein serine/threonine kinase activity of RAS85D:GTP:SRC42A:Phospho CNK:14-3-3epsilon dimer:Phospho PHL:Phospho KSR:14-3-3epsilon dimer:AVE:DSOR1:CK2:PAR-1:PP2A [plasma membrane]

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