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phospho-Vav [cytosol]
Stable Identifier
R-DME-437946
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
p-Y174-VAV1, Q9NHV9
Locations in the PathwayBrowser
Expand all
Drug ADME (Drosophila melanogaster)
Azathioprine ADME (Drosophila melanogaster)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
GPVI-mediated activation cascade (Drosophila melanogaster)
VAV1 is a GEF for Rho/Rac family GTPases (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
FCERI mediated MAPK activation (Drosophila melanogaster)
Activation of RAC1 by VAV (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
Autophosphorylation of PAK (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
Phosphorylation and activation of VAV (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
Recruitment of PAK to the membrane by binding active RAC1 (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VAV exchanges GTP for GDP on RAC1, activating it (Drosophila melanogaster)
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3 [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3 [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
PAK1-3 autophosphorylates (Drosophila melanogaster)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3 [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3 [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
PAK1-3 dimer disassociates (Drosophila melanogaster)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3 [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3 [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
RAC1 binds PAK1-3 (Drosophila melanogaster)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3 [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
p-VAV family:PIP3:RAC1:GTP [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3 [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
p-VAV family:PIP3 binds RAC1:GDP (Drosophila melanogaster)
p-VAV family:PIP3 [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Drosophila melanogaster)
p-VAV family:PIP3 [plasma membrane] (Drosophila melanogaster)
phospho-Vav [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9NHV9
Gene Names
Vav
Reference Genes
BioGPS Gene:32920 Vav
ENSEMBL:FBgn0040068
FlyBase:FBgn0040068
KEGG:dme:Dmel_CG7893 Vav
Monarch:32920 Vav
NCBI Gene:32920 Vav
UCSC:Q9NHV9 Vav
Reference Transcript
RefSeq:NM_167642.3 Vav
RefSeq:NM_133144.4 Vav
Other Identifiers
142127_at
151471_at
1635592_at
1636614_a_at
32920
GO:0001745
GO:0002009
GO:0002376
GO:0005085
GO:0005515
GO:0005737
GO:0005829
GO:0007010
GO:0007173
GO:0007298
GO:0007391
GO:0007409
GO:0007411
GO:0007417
GO:0007424
GO:0007520
GO:0009653
GO:0016043
GO:0016477
GO:0030036
GO:0031532
GO:0032956
GO:0035011
GO:0042059
GO:0043087
GO:0046872
GO:0048010
GO:0048468
GO:0048513
GO:0048856
GO:0048870
GO:0070374
GO:0072499
GO:0090630
GO:0098542
GO:0098772
GO:1903391
GO:2000251
Participates
as a component of
p-VAV family:PIP3 [plasma membrane] (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV [plasma membrane] (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
phospho-Vav [plasma membrane]
Vav [cytosol]
Vav [cytosol]
phospho-Vav [cytosol]
phospho-Vav [cytosol]
Vav [cytosol]
Vav [plasma membrane]
Inferred From
p-VAV family [cytosol]
(Homo sapiens)
p-VAV family [cytosol]
(Homo sapiens)
p-Y174-VAV1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 174 (in Homo sapiens)
Coordinate
174
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_573372.1
,
NP_728235.1
ENSEMBL
FBtr0074677
,
FBtr0074678
,
FBpp0074448
,
FBpp0074449
PRO
Q9NHV9
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