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PAK1 dimer [cytosol]
Stable Identifier
R-DME-445002
Type
Complex
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
EPHB-mediated forward signaling (Drosophila melanogaster)
PAK1 binds RAC1:GTP (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
L1CAM interactions (Drosophila melanogaster)
Signal transduction by L1 (Drosophila melanogaster)
Interaction of PAK1 with Rac1-GTP (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
Semaphorin interactions (Drosophila melanogaster)
Sema3A PAK dependent Axon repulsion (Drosophila melanogaster)
Activation of PAK by Rac1 (Drosophila melanogaster)
PAK1,2,3 dimer [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Regulation of T cell activation by CD28 family (Drosophila melanogaster)
Co-stimulation by CD28 (Drosophila melanogaster)
CD28 dependent Vav1 pathway (Drosophila melanogaster)
Activation of PAKs by RAC1 and CDC42 (Drosophila melanogaster)
PAK1,2,3 dimer [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
FCERI mediated MAPK activation (Drosophila melanogaster)
Autophosphorylation of PAK (Drosophila melanogaster)
PAK dimer [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Drosophila melanogaster)
PAK dimer [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
Recruitment of PAK to the membrane by binding active RAC1 (Drosophila melanogaster)
PAK dimer [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimer [plasma membrane] (Drosophila melanogaster)
PAK dimer [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
Fcgamma receptor (FCGR) dependent phagocytosis (Drosophila melanogaster)
Regulation of actin dynamics for phagocytic cup formation (Drosophila melanogaster)
RAC1 and CDC42 activate PAK1 (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK6/MAPK4 signaling (Drosophila melanogaster)
Activation of PAKs by RAC1 and CDC42 (Drosophila melanogaster)
PAK1,2,3 dimer [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
PAK1-3 autophosphorylates (Drosophila melanogaster)
PAK1,2,3 dimer [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
PAK1-3 dimer disassociates (Drosophila melanogaster)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Drosophila melanogaster)
PAK1,2,3 dimer [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RAC1 binds PAK1-3 (Drosophila melanogaster)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Drosophila melanogaster)
PAK1,2,3 dimer [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
PAK1,2,3 dimer [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases activate PAKs (Drosophila melanogaster)
NF2 binds PAK1 (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
PAK1:NF2 [plasma membrane] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RAC1 and CDC42 activate PAK1 (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RHO GTPase cycle (Drosophila melanogaster)
RAC1 GTPase cycle (Drosophila melanogaster)
RAC1 binds effectors at the plasma membrane (Drosophila melanogaster)
RAC1 effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RAC1:GTP:RAC1 effectors [plasma membrane] (Drosophila melanogaster)
RAC1 effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RAC2 GTPase cycle (Drosophila melanogaster)
RAC2 binds effectors at the plasma membrane (Drosophila melanogaster)
RAC2 plasma membrane effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Drosophila melanogaster)
RAC2 plasma membrane effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RAC3 GTPase cycle (Drosophila melanogaster)
RAC3 binds effectors at the plasma membrane (Drosophila melanogaster)
RAC3 effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RAC3:GTP:RAC3 effectors [plasma membrane] (Drosophila melanogaster)
RAC3 effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RHOH GTPase cycle (Drosophila melanogaster)
RHOH binds effectors at the plasma membrane (Drosophila melanogaster)
RHOH effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RHOH:GTP:RHOH effectors [plasma membrane] (Drosophila melanogaster)
RHOH effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RHOQ GTPase cycle (Drosophila melanogaster)
RHOQ binds effectors at the plasma membrane (Drosophila melanogaster)
RHOQ effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Drosophila melanogaster)
RHOQ effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RHOU GTPase cycle (Drosophila melanogaster)
RHOU binds effectors at the plasma membrane (Drosophila melanogaster)
RHOU effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RHOU:GTP:RHOU effectors [plasma membrane] (Drosophila melanogaster)
RHOU effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RHOV GTPase cycle (Drosophila melanogaster)
RHOV binds effectors at the plasma membrane (Drosophila melanogaster)
RHOV effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
RHOV:GTP:RHOV effectors [plasma membrane] (Drosophila melanogaster)
RHOV effectors [cytosol] (Drosophila melanogaster)
PAK1 dimer [cytosol] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
PAK1 [cytosol]
(Drosophila melanogaster)
Participates
as a member of
RHOV effectors [cytosol] (Drosophila melanogaster)
RHOQ effectors [cytosol] (Drosophila melanogaster)
RHOH effectors [cytosol] (Drosophila melanogaster)
CDC42 effectors [cytosol] (Drosophila melanogaster)
RAC2 plasma membrane effectors [cytosol] (Drosophila melanogaster)
RAC1 effectors [cytosol] (Drosophila melanogaster)
RHOJ effectors [cytosol] (Drosophila melanogaster)
RHOU effectors [cytosol] (Drosophila melanogaster)
PAK1,2,3 dimer [cytosol] (Drosophila melanogaster)
PAK dimer [cytosol] (Drosophila melanogaster)
as a candidate of
RAC3 effectors [cytosol] (Drosophila melanogaster)
as an input of
PAK1 binds RAC1:GTP (Drosophila melanogaster)
Interaction of PAK1 with Rac1-GTP (Drosophila melanogaster)
NF2 binds PAK1 (Drosophila melanogaster)
RAC1 and CDC42 activate PAK1 (Drosophila melanogaster)
as a component of
PAK1:NF2 [plasma membrane] (Drosophila melanogaster)
Inferred From
PAK1 dimer [cytosol]
(Homo sapiens)
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