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What is Reactome ?
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K63polyUb [cytosol]
Stable Identifier
R-DME-450152
Type
Polymer
Species
Drosophila melanogaster
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Signaling by Interleukins (Drosophila melanogaster)
Interleukin-1 family signaling (Drosophila melanogaster)
Interleukin-1 signaling (Drosophila melanogaster)
Pellino ubiquitinates IRAK1 (Drosophila melanogaster)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TRAF6 is K63 poly-ubiquitinated (Drosophila melanogaster)
hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
hp-IRAK1:3xTRAF6 binds UBE2N:UBE2V1:K63-polyUb (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
hp-IRAK1:3xTRAF6:3xUBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
hp-IRAK1:p-Pellino, IRAK4:p-Pellino bind UBE2N:UBE2V1 (Drosophila melanogaster)
IRAK1:Pellino:E2 complexes [cytosol] (Drosophila melanogaster)
IRAK4: p-Pellino-1,2,3:UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
hp-IRAK1: p-Pellino-1,2,(3):UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Interleukin-17 signaling (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Toll-like Receptor Cascades (Drosophila melanogaster)
Toll Like Receptor 10 (TLR10) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Toll Like Receptor 2 (TLR2) Cascade (Drosophila melanogaster)
Toll Like Receptor TLR1:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Toll Like Receptor TLR6:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Toll Like Receptor 3 (TLR3) Cascade (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Toll Like Receptor 4 (TLR4) Cascade (Drosophila melanogaster)
MyD88-independent TLR4 cascade (Drosophila melanogaster)
TRIF (TICAM1)-mediated TLR4 signaling (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Toll Like Receptor 5 (TLR5) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Toll Like Receptor 9 (TLR9) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Ubiquitination of IKBKG by TRAF6 (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Deubiquitination (Drosophila melanogaster)
Josephin domain DUBs (Drosophila melanogaster)
ATXN3 family cleave Ub chains (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
PARK2 autoubiquitinates (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Metalloprotease DUBs (Drosophila melanogaster)
PSMD14 cleaves K63-linked ubiquitin (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
STAMBPL1 is a deubiquitinase (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Ovarian tumor domain proteases (Drosophila melanogaster)
TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Ub-specific processing proteases (Drosophila melanogaster)
CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
USP13 deubiquitinates BECN1,USP10 (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
USP17 deubiquitinates RCE1, CDC25A, DDX58, IFIH1 (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
USP20, USP33 deubiquitinate ADRB2 (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
USP21 deubiquitinates RIPK1,DDX58 (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
USP33 deubiquitinates CCP110,ARRB (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
USP5 cleaves polyubiquitin (Drosophila melanogaster)
USP5:PolyUb [cytosol] (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
RAS processing (Drosophila melanogaster)
USP17L2 deubiquitinates RCE1 (Drosophila melanogaster)
PolyUb [cytosol] (Drosophila melanogaster)
K63polyUb [cytosol] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
repeated unit
K63-Ub [cytosol]
(Drosophila melanogaster)
Participates
as an output of
TNFAIP3 (A20) deubiquitinates K63polyUb-RIPK1 (Drosophila melanogaster)
TNFAIP3 in OTUD7B:TNFAIP3:ZRANB1 deubiquitinates K63polyUb-TRAF6 (Drosophila melanogaster)
USP13 deubiquitinates BECN1,USP10 (Drosophila melanogaster)
CYLD deubiquitinates K63polyUb-TRAF2,K63polyUb-TRAF6,K63polyUb-RIPK1,K63polyUb-IKBKG (Drosophila melanogaster)
ATXN3 family cleave Ub chains (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Drosophila melanogaster)
Activated TRAF6 synthesizes unanchored polyubiquitin chains (Drosophila melanogaster)
as an input of
STAMBPL1 is a deubiquitinase (Drosophila melanogaster)
PSMD14 cleaves K63-linked ubiquitin (Drosophila melanogaster)
ATXN3 family cleave Ub chains (Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Drosophila melanogaster)
Pellino ubiquitinates hp-IRAK1 (Drosophila melanogaster)
as a component of
UBE2N:UBE2V1:K63polyUb [cytosol] (Drosophila melanogaster)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [cytosol] (Drosophila melanogaster)
as a member of
PolyUb [cytosol] (Drosophila melanogaster)
Inferred From
Short K63polyUb [cytosol]
(Homo sapiens)
K63polyUb [cytosol]
(Homo sapiens)
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