YKI binds to HPO homodimer

Stable Identifier
R-DME-451858
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
cytosol
ReviewStatus
5/5
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YKI binds to HPO homodimer
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Yorkie (YKI), which has two WW domains, binds to Hippo (HPO) homodimer PPXY sequence motif, of which HPO has one per monomer unit. YKI remains in the cytosol where it is unable to activate its target genes.
Literature References
PubMed ID Title Journal Year
19733165 Phosphorylation-independent repression of Yorkie in Fat-Hippo signaling

Oh, H, Irvine, KD, Reddy, BV

Dev Biol 2009
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Authored
Williams, MG  (2010-01-14)
Reviewed
Irvine, KD  (2009-11-25)
Created
Williams, MG  (2010-01-14)
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