Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
dsh [cytosol]
Stable Identifier
R-DME-4641157
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
ub-DVL1, P51140
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
TCF dependent signaling in response to WNT (Drosophila melanogaster)
Degradation of DVL (Drosophila melanogaster)
DVL1 is ubiquitinated by HECW1 (Drosophila melanogaster)
ub-DVL1:HECW1 [cytosol] (Drosophila melanogaster)
dsh [cytosol] (Drosophila melanogaster)
Ubiquitinated DVL1 is degraded by the proteasome (Drosophila melanogaster)
ub-DVL1:HECW1 [cytosol] (Drosophila melanogaster)
dsh [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P51140 dsh
Gene Names
dsh, CG18361
Chain
chain:1-623
Reference Genes
BioGPS Gene:32078 dsh
CTD Gene:32078 dsh
KEGG Gene (Drosophila melanogaster):Dmel_CG18361 dsh
Monarch:32078 dsh
NCBI Gene:32078 dsh
UCSC:P51140 dsh
Reference Transcript
RefSeq:NM_078563.3 dsh
Other Identifiers
143133_at
1628788_a_at
32078
GO:0000132
GO:0000278
GO:0001736
GO:0001737
GO:0001745
GO:0001751
GO:0005109
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0007010
GO:0007163
GO:0007298
GO:0007367
GO:0007391
GO:0007435
GO:0008045
GO:0008289
GO:0008585
GO:0008587
GO:0016020
GO:0016055
GO:0016201
GO:0016477
GO:0019904
GO:0022414
GO:0023052
GO:0030154
GO:0030159
GO:0030707
GO:0031290
GO:0032231
GO:0035019
GO:0035159
GO:0035309
GO:0035317
GO:0035556
GO:0042067
GO:0043226
GO:0045179
GO:0045773
GO:0048076
GO:0048477
GO:0048675
GO:0048730
GO:0048856
GO:0048870
GO:0050770
GO:0060070
GO:0060090
GO:0060250
GO:0060914
GO:0070300
GO:0090163
GO:1902669
GO:1990909
Participates
as a component of
ub-DVL1:HECW1 [cytosol] (Drosophila melanogaster)
Other forms of this molecule
dsh [cytosol]
dsh [cytosol]
dsh [cytosol]
dsh [cytosol]
dsh [cytosol]
phospho-dsh [clathrin-coated endocytic vesicle]
DSH [cytosol]
phospho-dsh [cytosol]
phospho-dsh [cytosol]
phospho-dsh [cytosol]
phospho-dsh [cytosol]
phospho-dsh [cytosol]
phospho-dsh [cytosol]
Inferred From
ub-DVL1 [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at unknown position
Modification
K48polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_511118.2
Flybase
FBgn0000499
PRO
P51140
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VVV9 NKD
0.842
10
UniProt:Q95TT5 Q95TT5
0.691
4
UniProt:P07207 N
7
Elongated Fucose N [plasma membrane]
(R-DME-206245)
Fucose N [plasma membrane]
(R-DME-205885)
Notch NICD fragment [cytosol]
(R-DME-177092)
Notch NICD fragment [nucleoplasm]
(R-DME-177090)
Glc,Fuc-N [endoplasmic reticulum lumen]
(R-DME-2032242)
Glc,Fuc-N [Golgi lumen]
(R-DME-2032747)
Glc,Fuc-N [plasma membrane]
(R-DME-2071837)
0.671
4
UniProt:P00522 Abl
8
ABL_DROME [cytosol]
(R-DME-428864)
ABL2 [cytosol]
(R-DME-375998)
phospho-p-Y393-ABL1 [cytosol]
(R-DME-9865161)
p-Y226,Y393-ABL1 [nucleoplasm]
(R-DME-8985251)
ABL1 [cytosol]
(R-DME-375987)
p-Y226,Y393-ABL1 [cytosol]
(R-DME-8942610)
ABL1 [nucleoplasm]
(R-DME-5686579)
phospho-p-S456-ABL1 [nucleoplasm]
(R-DME-5686576)
0.602
6
UniProt:P18537 fz
7
FZ [plasma membrane]
(R-DME-205850)
fz [clathrin-coated endocytic vesicle membrane]
(R-DME-5140723)
fz [plasma membrane]
(R-DME-517394)
fz [plasma membrane]
(R-DME-205974)
fz [plasma membrane]
(R-DME-443945)
fz [plasma membrane]
(R-DME-443948)
fz [plasma membrane]
(R-DME-443950)
0.598
3
UniProt:Q7JUF2 dgo
1
DGO [cytosol]
(R-DME-351073)
0.581
5
UniProt:Q7YZA4 Q7YZA4
0.537
3
UniProt:Q99MH6 NKD1
0.508
2
UniProt:P83949 UBX
0.482
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text