Reactome | Diap1 [cytosol]

Diap1 [cytosol]

Stable Identifier

R-DME-50845

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

BIRC3, Q24306

Locations in the PathwayBrowser

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Programmed Cell Death (Drosophila melanogaster)

- Regulated Necrosis (Drosophila melanogaster)
  - RIPK1-mediated regulated necrosis (Drosophila melanogaster)
    - Regulation of necroptotic cell death (Drosophila melanogaster)
      - BIRC2/3 (cIAP1/2) is autoubiquitinated (Drosophila melanogaster)
        
        BIRC2,3,4 [cytosol] (Drosophila melanogaster)
        
        Homologues of BIRC3 [cytosol] (Drosophila melanogaster)
        
        Diap1 [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q24306 Diap1

Gene Names

Diap1, Iap1, th, CG12284

Chain

chain:1-438

Reference Genes

BioGPS Gene:39753 Diap1

CTD Gene:39753 Diap1

KEGG:dme:Dmel_CG12284 Diap1

Monarch:39753 Diap1

NCBI Gene:39753 Diap1

UCSC:Q24306 Diap1

Reference Transcript

Other Identifiers

152631_at

1636787_s_at

39753

GO:0000209

GO:0003824

GO:0004842

GO:0004869

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0006915

GO:0007283

GO:0007289

GO:0007298

GO:0008270

GO:0010604

GO:0016055

GO:0016740

GO:0022414

GO:0022416

GO:0031398

GO:0031624

GO:0031625

GO:0043027

GO:0043066

GO:0044390

GO:0045035

GO:0045116

GO:0045752

GO:0046329

GO:0046673

GO:0046872

GO:0048471

GO:0048800

GO:0048856

GO:0048870

GO:0051726

GO:0051865

GO:0061630

GO:0061663

GO:0070936

GO:0089720

GO:0090263

GO:0098772

GO:0140096

GO:1903688

GO:1990381

Participates

as a member of

Homologues of BIRC3 [cytosol] (Drosophila melanogaster)

Other forms of this molecule

Diap1 [cytosol]

Diap1 [nucleoplasm]

TH [cytosol]

Phospho TH [cytosol]

Inferred From

BIRC3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001261916.1, NP_001261917.1, NP_730098.1, NP_730097.1, NP_001261918.1, NP_524101.2

ENSEMBL

FBpp0075255, FBpp0075256, FBpp0075254, FBpp0305795, FBpp0305793, FBpp0305794, FBtr0075500, FBtr0075499, FBtr0075501, FBtr0333619, FBtr0333618, FBgn0260635, FBtr0333617

PRO

Q24306

FlyBase

FBgn0260635

PDB

3SIP, 1SE0, 1JD4, 1Q4Q, 1JD5, 1JD6, 1SDZ, 3SIQ

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9XYF4	1	Dronc [cytosol] (R-DME-5657970)	0.908	11
UniProt:Q24106 HID			0.87	9
UniProt:Q24475 RPR			0.87	9
UniProt:Q9V3Y8	5	phospho-IKKepsilon [cytosol] (R-DME-9008705) phospho-IKKepsilon [cytosol] (R-DME-450278) IKKepsilon [cytosol] (R-DME-450225) IKKepsilon [cytosol] (R-DME-166267) phospho-IKKepsilon [cytosol] (R-DME-168379)	0.602	3
UniProt:O01382	20	Drice [cytosol] (R-DME-57031) Drice [cytosol] (R-DME-933453) Drice [cytosol] (R-DME-75975) Drice [cytosol] (R-DME-76158) Drice [cytosol] (R-DME-3465357) Drice [cytosol] (R-DME-3371356) Drice [cytosol] (R-DME-3465408) Drice [mitochondrial outer membrane] (R-DME-351828) Drice [mitochondrial outer membrane] (R-DME-351869) Drice [cytosol] (R-DME-141646) Drice [cytosol] (R-DME-141644) Drice [nucleoplasm] (R-DME-211203) Drice [nucleoplasm] (R-DME-211194) Drice [cytosol] (R-DME-141642) Drice [cytosol] (R-DME-141641) Drice [cytosol] (R-DME-57021) Drice [cytosol] (R-DME-57029) Drice [cytosol] (R-DME-266128) Drice [cytosol] (R-DME-350313) Drice [nucleoplasm] (R-DME-351924)	0.544	3
UniProt:O02002	20	Dcp-1 [cytosol] (R-DME-3465483-2) Dcp-1 [cytosol] (R-DME-3465404-2) Dcp-1 [cytosol] (R-DME-9818805-2) Dcp-1 [nucleoplasm] (R-DME-352246-2) Dcp-1 [nucleoplasm] (R-DME-352247-2) Dcp-1 [nucleoplasm] (R-DME-351927-2) Dcp-1 [nucleoplasm] (R-DME-351924-2) Dcp-1 [cytosol] (R-DME-350313-2) Dcp-1 [cytosol] (R-DME-266128-2) Dcp-1 [cytosol] (R-DME-57029-2) Dcp-1 [cytosol] (R-DME-57021-2) Dcp-1 [cytosol] (R-DME-141641-2) Dcp-1 [cytosol] (R-DME-141642-2) Dcp-1 [nucleoplasm] (R-DME-211194-2) Dcp-1 [nucleoplasm] (R-DME-211203-2) Dcp-1 [cytosol] (R-DME-141644-2) Dcp-1 [cytosol] (R-DME-141646-2) Dcp-1 [mitochondrial outer membrane] (R-DME-351869-2) Dcp-1 [mitochondrial outer membrane] (R-DME-351828-2) Dcp-1 [cytosol] (R-DME-3465408-2)	0.534	2

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