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K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane]
Stable Identifier
R-DME-5205659
Type
Complex
Species
Drosophila melanogaster
Compartment
mitochondrial outer membrane
Locations in the PathwayBrowser
Expand all
Autophagy (Drosophila melanogaster)
Macroautophagy (Drosophila melanogaster)
Selective autophagy (Drosophila melanogaster)
Mitophagy (Drosophila melanogaster)
PINK1-PRKN Mediated Mitophagy (Drosophila melanogaster)
LC3 binds the autophagosome membrane Atg5-Atg12 complex (Drosophila melanogaster)
ATG5:ATG12:LC3:K48polyUB Mitophagy Substrates:SQSTM1 [phagocytic vesicle] (Drosophila melanogaster)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Drosophila melanogaster)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Drosophila melanogaster)
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Drosophila melanogaster)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Drosophila melanogaster)
p62 binds ubiquitinated mitochondrial substrates (Drosophila melanogaster)
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Homologues of K48polyUb-MFN2 [mitochondrial outer membrane]
(Drosophila melanogaster)
Homologues of K48polyUb-VDAC1 [mitochondrial outer membrane]
(Drosophila melanogaster)
K48polyUb-MFN1 [mitochondrial outer membrane]
(Drosophila melanogaster)
mTerf3 [mitochondrial outer membrane]
(Drosophila melanogaster)
SQSTM1 [cytosol]
(Drosophila melanogaster)
Participates
as an output of
p62 binds ubiquitinated mitochondrial substrates (Drosophila melanogaster)
as a component of
LC3:K48polyUB Mitophagy Substrates:SQSTM1 [cytosol] (Drosophila melanogaster)
Inferred From
K48polyUB Mitophagy Substrates:SQSTM1 [mitochondrial outer membrane]
(Homo sapiens)
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