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spel1 [nucleoplasm]
Stable Identifier
R-DME-5357525
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
MSH2, P43248
Locations in the PathwayBrowser
Expand all
DNA Repair (Drosophila melanogaster)
Mismatch Repair (Drosophila melanogaster)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Drosophila melanogaster)
EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Drosophila melanogaster)
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
Formation of MSH2:MSH6 Complex (Drosophila melanogaster)
MSH2:MSH6:ADP [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Drosophila melanogaster)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6 binds 1 base mismatch or 1-2 base insertion/deletion loop (Drosophila melanogaster)
MSH2:MSH6:ADP [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ADP [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6 exchanges ADP for ATP (Drosophila melanogaster)
MSH2:MSH6:ADP:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ADP [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Drosophila melanogaster)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP:DNA containing 1-2 base mismatch [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
spel1 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P43248
Gene Names
spel1
Reference Genes
BioGPS Gene:34842 spel1
CTD Gene:34842 spel1
ENSEMBL:FBgn0015546
FlyBase:FBgn0015546
KEGG:dme:Dmel_CG4215 spel1
Monarch:34842 spel1
NCBI Gene:34842 spel1
UCSC:P43248 spel1
Reference Transcript
RefSeq:NM_001014482.3 spel1
RefSeq:NM_001259102.2 spel1
RefSeq:NM_078841.5 spel1
RefSeq:NM_001299002.1 spel1
Other Identifiers
143816_at
1630496_a_at
34842
GO:0000166
GO:0003677
GO:0005524
GO:0005634
GO:0006281
GO:0006298
GO:0006301
GO:0006310
GO:0006312
GO:0006974
GO:0016787
GO:0016887
GO:0030983
GO:0032301
GO:0036297
GO:0043570
GO:0140664
Participates
as a component of
MSH2:MSH6:ATP [nucleoplasm] (Drosophila melanogaster)
MSH2:MSH6:ADP [nucleoplasm] (Drosophila melanogaster)
as an input of
Formation of MSH2:MSH6 Complex (Drosophila melanogaster)
Inferred From
MSH2 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001246031.1
,
NP_523565.2
,
NP_001014482.2
,
NP_001285931.1
ENSEMBL
FBgn0015546
,
FBpp0310470
,
FBtr0344019
,
FBtr0344018
,
FBpp0080203
,
FBtr0080630
,
FBtr0309281
,
FBpp0301208
,
FBpp0310469
FlyBase
FBgn0015546
PRO
P43248
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