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Dmel\CG6766 [endoplasmic reticulum quality control compartment]
Stable Identifier
R-DME-5362354
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
endoplasmic reticulum quality control compartment
Synonyms
ERLEC1, Q9VKC7
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by Hedgehog (Drosophila melanogaster)
Hedgehog ligand biogenesis (Drosophila melanogaster)
C-terminal Hh fragments are bound by lectins (Drosophila melanogaster)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Drosophila melanogaster)
Dmel\CG6766 [endoplasmic reticulum quality control compartment] (Drosophila melanogaster)
Dmel\CG6766 [endoplasmic reticulum quality control compartment] (Drosophila melanogaster)
C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Drosophila melanogaster)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Drosophila melanogaster)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Drosophila melanogaster)
Dmel\CG6766 [endoplasmic reticulum quality control compartment] (Drosophila melanogaster)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Drosophila melanogaster)
Dmel\CG6766 [endoplasmic reticulum quality control compartment] (Drosophila melanogaster)
SYVN1 ubiquitinates Hh C-terminal fragments (Drosophila melanogaster)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Drosophila melanogaster)
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Drosophila melanogaster)
Dmel\CG6766 [endoplasmic reticulum quality control compartment] (Drosophila melanogaster)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Drosophila melanogaster)
Dmel\CG6766 [endoplasmic reticulum quality control compartment] (Drosophila melanogaster)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Drosophila melanogaster)
Dmel\CG6766 [endoplasmic reticulum quality control compartment] (Drosophila melanogaster)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Drosophila melanogaster)
Dmel\CG6766 [endoplasmic reticulum quality control compartment] (Drosophila melanogaster)
Transport of small molecules (Drosophila melanogaster)
ABC-family proteins mediated transport (Drosophila melanogaster)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Drosophila melanogaster)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Drosophila melanogaster)
ERAD complex [endoplasmic reticulum membrane] (Drosophila melanogaster)
Dmel\CG6766 [endoplasmic reticulum quality control compartment] (Drosophila melanogaster)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Drosophila melanogaster)
ERAD complex [endoplasmic reticulum membrane] (Drosophila melanogaster)
Dmel\CG6766 [endoplasmic reticulum quality control compartment] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VKC7
Gene Names
Dmel\CG6766
Reference Genes
BioGPS Gene:34619 Dmel\CG6766
ENSEMBL:FBgn0032398
FlyBase:FBgn0032398
KEGG Gene (Drosophila melanogaster):Dmel_CG6766 Dmel\CG6766
Monarch:34619 Dmel\CG6766
NCBI Gene:34619 Dmel\CG6766
UCSC:Q9VKC7 Dmel\CG6766
Reference Transcript
RefSeq:NM_135693.2 Dmel\CG6766
Other Identifiers
142421_at
1631745_at
34619
GO:0005783
GO:0005788
GO:0006886
GO:0012505
GO:0023052
GO:0030163
GO:0030433
GO:0030968
GO:0030970
GO:0043226
Participates
as an output of
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Drosophila melanogaster)
as an input of
C-terminal Hh fragments are bound by lectins (Drosophila melanogaster)
as a component of
C-terminal Hh fragments:OS9/ERLEC1 [endoplasmic reticulum lumen] (Drosophila melanogaster)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Drosophila melanogaster)
ERAD complex [endoplasmic reticulum membrane] (Drosophila melanogaster)
Inferred From
OS9/ERLEC1 [endoplasmic reticulum quality control compartment]
(Homo sapiens)
ERLEC1 [endoplasmic reticulum quality control compartment]
(Homo sapiens)
Cross References
RefSeq
NP_609537.1
Flybase
FBgn0032398
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