Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
CHOL-N-palmitoyl-L-cysteine-SHH(24-197) [plasma membrane]
Stable Identifier
R-DME-5362407
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
plasma membrane
Synonyms
Q02936
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Signaling by Hedgehog (Drosophila melanogaster)
Hedgehog ligand biogenesis (Drosophila melanogaster)
Hh-Np traffics to the plasma membrane (Drosophila melanogaster)
Hh-Np [plasma membrane] (Drosophila melanogaster)
CHOL-N-palmitoyl-L-cysteine-SHH(24-197) [plasma membrane] (Drosophila melanogaster)
Release of Hh-Np from the secreting cell (Drosophila melanogaster)
Hh-Np binds GPC5 (Drosophila melanogaster)
Hh-Np [plasma membrane] (Drosophila melanogaster)
CHOL-N-palmitoyl-L-cysteine-SHH(24-197) [plasma membrane] (Drosophila melanogaster)
Hh-Np:GPI-GPC5 [plasma membrane] (Drosophila melanogaster)
Hh-Np [plasma membrane] (Drosophila melanogaster)
CHOL-N-palmitoyl-L-cysteine-SHH(24-197) [plasma membrane] (Drosophila melanogaster)
NOTUM releases Hh-Np:GPC5 from the plasma membrane (Drosophila melanogaster)
Hh-Np:GPI-GPC5 [plasma membrane] (Drosophila melanogaster)
Hh-Np [plasma membrane] (Drosophila melanogaster)
CHOL-N-palmitoyl-L-cysteine-SHH(24-197) [plasma membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q02936 hh
Gene Names
hh, CG4637
Chain
signal peptide:1-, propeptide:-84, chain:85-471, chain:85-257
Reference Genes
BioGPS Gene:42737 hh
KEGG:dme:Dmel_CG4637 hh
Monarch:42737 hh
NCBI Gene:42737 hh
UCSC:Q02936 hh
Reference Transcript
RefSeq:NM_001038976.1 hh
Other Identifiers
143501_at
1626527_at
42737
GO:0001708
GO:0001745
GO:0001746
GO:0001751
GO:0002052
GO:0002376
GO:0002385
GO:0003824
GO:0005113
GO:0005509
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005768
GO:0005829
GO:0005886
GO:0006508
GO:0007224
GO:0007267
GO:0007275
GO:0007280
GO:0007346
GO:0007367
GO:0007386
GO:0007418
GO:0007427
GO:0007440
GO:0007442
GO:0007446
GO:0007458
GO:0007473
GO:0007476
GO:0007478
GO:0007487
GO:0007506
GO:0007507
GO:0008233
GO:0008347
GO:0008354
GO:0008544
GO:0009653
GO:0009880
GO:0010468
GO:0016015
GO:0016335
GO:0016539
GO:0016540
GO:0016740
GO:0016787
GO:0022414
GO:0023052
GO:0030139
GO:0030154
GO:0031410
GO:0034111
GO:0035154
GO:0035215
GO:0035217
GO:0035222
GO:0035224
GO:0035231
GO:0035232
GO:0035277
GO:0035288
GO:0035289
GO:0035290
GO:0043226
GO:0045168
GO:0045861
GO:0046872
GO:0048018
GO:0048066
GO:0048099
GO:0048100
GO:0048731
GO:0048856
GO:0048870
GO:0051604
GO:0060914
GO:0097264
GO:0098772
GO:0140096
GO:0140853
GO:2000010
GO:2000274
GO:2000495
Participates
as a member of
Hh-Np [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
IHH [extracellular region]
DHH(33-?) [extracellular region]
SHH(34-?) [extracellular region]
N4glycoAsn-2xHC-DHH(23-396) [endoplasmic reticulum lumen]
N4glycoAsn-2xHC-IHH(28-411) [endoplasmic reticulum lumen]
N4glycoAsn-2xHC-SHH(24-462) [endoplasmic reticulum lumen]
CHOL-DHH(23-198) [endoplasmic reticulum lumen]
CHOL-IHH(28-202) [endoplasmic reticulum lumen]
CHOL-SHH(24-197) [endoplasmic reticulum lumen]
N4glycoAsn-IHH(203-411) [endoplasmic reticulum lumen]
N4glycoAsn-DHH(199-396) [endoplasmic reticulum lumen]
N4glycoAsn-SHH(198-462) [endoplasmic reticulum lumen]
2xHC-DHH(23-396) [endoplasmic reticulum lumen]
2xHC-IHH(28-411) [endoplasmic reticulum lumen]
2xHC-SHH(24-462) [endoplasmic reticulum lumen]
ub-N4glycoAsn-DHH(199-396) [cytosol]
ub-N4glycoAsn-IHH(203-411) [cytosol]
ub-N4glycoAsn-SHH(198-462) [cytosol]
ub-N4glycoAsn-IHH(203-411) [endoplasmic reticulum lumen]
ub-N4glycoAsn-DHH(199-396) [endoplasmic reticulum lumen]
ub-N4glycoAsn-SHH(198-462) [endoplasmic reticulum lumen]
CHOL-N-palmitoyl-L-cysteine-DHH(23-198) [endoplasmic reticulum lumen]
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [endoplasmic reticulum lumen]
CHOL-N-palmitoyl-L-cysteine-SHH(24-197) [endoplasmic reticulum lumen]
CHOL-N-palmitoyl-L-cysteine-DHH(23-198) [plasma membrane]
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [plasma membrane]
CHOL-N-palmitoyl-L-cysteine-DHH(23-198) [extracellular region]
CHOL-N-palmitoyl-L-cysteine-IHH(28-202) [extracellular region]
CHOL-N-palmitoyl-L-cysteine-SHH(24-197) [extracellular region]
HH [cytosol]
N-HH [cytosol]
C-HH [cytosol]
N-HH [extracellular region]
Inferred From
CHOL-N-palmitoyl-L-cysteine-SHH(24-197) [plasma membrane]
(Homo sapiens)
Modified Residues
Name
glycine cholesterol ester at 197 (in Homo sapiens)
Coordinate
197
PsiMod Name
glycine cholesterol ester [MOD:00314]
PsiMod Definition
A protein modification that effectively converts a glycine residue to glycine cholesterol ester.
Name
N-palmitoyl-L-cysteine at 24 (in Homo sapiens)
Coordinate
24
PsiMod Name
N-palmitoyl-L-cysteine [MOD:00069]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to N-palmitoyl-L-cysteine.
Cross References
RefSeq
NP_001034065.1
ENSEMBL
FBtr0100506
,
FBpp0099945
FlyBase
FBgn0004644
PRO
Q02936
PDB
6TD6
,
6TYY
,
2IBG
,
1AT0
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text