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Prp19 [nucleoplasm]
Stable Identifier
R-DME-5420907
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
PRPF19, Q7KLW9
Locations in the PathwayBrowser
Expand all
DNA Repair (Drosophila melanogaster)
Nucleotide Excision Repair (Drosophila melanogaster)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Drosophila melanogaster)
Dual incision in TC-NER (Drosophila melanogaster)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Drosophila melanogaster)
TC-NER incision complex [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Drosophila melanogaster)
TC-NER incision complex [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Drosophila melanogaster)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Drosophila melanogaster)
TC-NER pre-incision complex [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Drosophila melanogaster)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
Formation of TC-NER Pre-Incision Complex (Drosophila melanogaster)
UVSSA:USP7 deubiquitinates ERCC6 (Drosophila melanogaster)
TC-NER pre-incision complex [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
Gap-filling DNA repair synthesis and ligation in TC-NER (Drosophila melanogaster)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Drosophila melanogaster)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Drosophila melanogaster)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
Metabolism of RNA (Drosophila melanogaster)
Processing of Capped Intron-Containing Pre-mRNA (Drosophila melanogaster)
mRNA Splicing (Drosophila melanogaster)
mRNA Splicing - Major Pathway (Drosophila melanogaster)
Formation of the Spliceosomal C complex containing intron lariat (Drosophila melanogaster)
Spliceosomal B* complex [nucleoplasm] (Drosophila melanogaster)
PRP19-CDC5L complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
Spliceosomal C complex [nucleoplasm] (Drosophila melanogaster)
PRP19-CDC5L complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
Formation of the Spliceosomal C* complex (Drosophila melanogaster)
Spliceosomal C complex [nucleoplasm] (Drosophila melanogaster)
PRP19-CDC5L complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
PRP19-CDC5L complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
Formation of the Spliceosomal P complex and exon ligation (Drosophila melanogaster)
Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
PRP19-CDC5L complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
Spliceosomal P complex [nucleoplasm] (Drosophila melanogaster)
PRP19-CDC5L complex [nucleoplasm] (Drosophila melanogaster)
Prp19 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7KLW9
Gene Names
Prp19
Reference Genes
BioGPS Gene:37123 Prp19
CTD Gene:37123 Prp19
ENSEMBL:FBgn0261119
FlyBase:FBgn0261119
KEGG:dme:Dmel_CG5519 Prp19
Monarch:37123 Prp19
NCBI Gene:37123 Prp19
UCSC:Q7KLW9 Prp19
Reference Transcript
RefSeq:NM_079059.3 Prp19
Other Identifiers
143730_at
1622980_at
37123
GO:0000381
GO:0000398
GO:0000974
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0005737
GO:0006281
GO:0006325
GO:0006397
GO:0008380
GO:0016071
GO:0016567
GO:0016740
GO:0043226
GO:0061630
GO:0070534
GO:0071006
GO:0071011
GO:0071013
GO:0140096
Participates
as a component of
PRP19-CDC5L complex [nucleoplasm] (Drosophila melanogaster)
XAB2 complex [nucleoplasm] (Drosophila melanogaster)
Inferred From
PRPF19 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_523783.1
ENSEMBL
FBpp0085902
,
FBtr0086723
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