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POLQ [nucleoplasm]
Stable Identifier
R-DME-5687494
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
O18475
Locations in the PathwayBrowser
Expand all
DNA Repair (Drosophila melanogaster)
DNA Double-Strand Break Repair (Drosophila melanogaster)
Homology Directed Repair (Drosophila melanogaster)
HDR through MMEJ (alt-NHEJ) (Drosophila melanogaster)
PARP1 or PARP2, FEN1 and POLQ are recruited to MMEJ site (Drosophila melanogaster)
Annealed microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Drosophila melanogaster)
POLQ homodimer [nucleoplasm] (Drosophila melanogaster)
POLQ [nucleoplasm] (Drosophila melanogaster)
POLQ homodimer [nucleoplasm] (Drosophila melanogaster)
POLQ [nucleoplasm] (Drosophila melanogaster)
PARP1,PARP2 dimers bound to MMEJ sites autoPARylate (Drosophila melanogaster)
Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Drosophila melanogaster)
POLQ homodimer [nucleoplasm] (Drosophila melanogaster)
POLQ [nucleoplasm] (Drosophila melanogaster)
POLQ homodimer [nucleoplasm] (Drosophila melanogaster)
POLQ [nucleoplasm] (Drosophila melanogaster)
POLQ extends annealed 3'-ssDNA overhangs in MMEJ (Drosophila melanogaster)
Annealed microhomologous 3'-ssDNA overhangs-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Drosophila melanogaster)
POLQ homodimer [nucleoplasm] (Drosophila melanogaster)
POLQ [nucleoplasm] (Drosophila melanogaster)
Extended microhomologous 3'-ssDNA overhangs-flap-DSB:MRN:RBBP8:PARP1,PARP2:FEN1:POLQ [nucleoplasm] (Drosophila melanogaster)
POLQ homodimer [nucleoplasm] (Drosophila melanogaster)
POLQ [nucleoplasm] (Drosophila melanogaster)
POLQ homodimer [nucleoplasm] (Drosophila melanogaster)
POLQ [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:O18475
Reference Genes
BioGPS Gene:41571
ENSEMBL:FBgn0002905
FlyBase:FBgn0002905
KEGG:dme:Dmel_CG6019
Monarch:41571
NCBI Gene:41571
UCSC:O18475
Reference Transcript
RefSeq:NM_079609.3
Other Identifiers
142745_at
1635214_at
41571
GO:0000731
GO:0003676
GO:0003677
GO:0003824
GO:0003887
GO:0005524
GO:0005634
GO:0006260
GO:0006261
GO:0006281
GO:0006302
GO:0016740
GO:0016787
GO:0016829
GO:0017116
GO:0031297
GO:0032508
GO:0043226
GO:0051575
GO:0071897
GO:0097681
GO:0140097
GO:0140657
GO:1901255
Participates
as a component of
POLQ homodimer [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
POLN [nucleoplasm]
Inferred From
POLQ [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_524333.1
ENSEMBL
FBtr0082662
,
FBpp0082131
PRO
O18475
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