Reactome | Spn28Dc [endoplasmic reticulum-Golgi intermediate compartment membrane]

Spn28Dc [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-DME-5689734-25

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

(Glc)3(GlcNAc)2(Man)9-SERPINA1, Q9VLU4

Locations in the PathwayBrowser

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Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - Asparagine N-linked glycosylation (Drosophila melanogaster)
    - Transport to the Golgi and subsequent modification (Drosophila melanogaster)
      - ER to Golgi Anterograde Transport (Drosophila melanogaster)
        
        COPII-mediated vesicle transport (Drosophila melanogaster)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Drosophila melanogaster)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Spn28Dc [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

Vesicle-mediated transport (Drosophila melanogaster)

- Membrane Trafficking (Drosophila melanogaster)
  - ER to Golgi Anterograde Transport (Drosophila melanogaster)
    - COPII-mediated vesicle transport (Drosophila melanogaster)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Drosophila melanogaster)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Spn28Dc [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VLU4

Gene Names

Spn28Dc

Reference Genes

BioGPS Gene:34091 Spn28Dc

ENSEMBL:FBgn0031973

Flybase:FBgn0031973

KEGG Gene (Drosophila melanogaster):Dmel_CG7219 Spn28Dc

Monarch:34091 Spn28Dc

NCBI Gene:34091 Spn28Dc

UCSC:Q9VLU4 Spn28Dc

Reference Transcript

RefSeq:NM_135328.3 Spn28Dc

Other Identifiers

146000_at

1636145_at

34091

GO:0002376

GO:0003674

GO:0004867

GO:0005575

GO:0005576

GO:0005615

GO:0006950

GO:0007275

GO:0008150

GO:0009058

GO:0009611

GO:0010466

GO:0010951

GO:0019748

GO:0030234

GO:0030414

GO:0035009

GO:0042438

GO:0045861

GO:0048856

Participates

as a member of

Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

Other forms of this molecule

Spn28Dc [extracellular region]

Spn28Dc [platelet alpha granule lumen]

Spn28Dc [extracellular region]

Spn28Dc [endoplasmic reticulum lumen]

phospho-Spn28Dc [endoplasmic reticulum lumen]

Spn28Dc [endoplasmic reticulum lumen]

Spn28Dc [COPII-coated ER to Golgi transport vesicle]

Spn28Dc [ficolin-1-rich granule lumen]

Spn28Dc [extracellular region]

Spn28Dc [secretory granule membrane]

Spn28Dc [plasma membrane]

Spn28Dc [secretory granule lumen]

Spn28Dc [extracellular region]

Spn28Dc [ficolin-1-rich granule membrane]

Spn28Dc [plasma membrane]

Spn28Dc [azurophil granule lumen]

Spn28Dc [extracellular region]

Spn28Dc [lysosomal lumen]

Spn28Dc [extracellular region]

Spn28Dc [endoplasmic reticulum lumen]

Spn28Dc [extracellular region]

Spn28Dc [endoplasmic reticulum lumen]

Spn28Dc [platelet dense granule lumen]

Spn28Dc [extracellular region]

Inferred From

(Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Modified Residues

Name

N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position

Modification

N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)

PsiMod Name

N4-(N-acetylamino)glucosyl-L-asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.

Cross References

RefSeq

NP_609172.1

Flybase

FBgn0031973

PRO

Q9VLU4