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POLR2A [nucleoplasm]
Stable Identifier
R-DME-63502
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
P04052
Locations in the PathwayBrowser
Expand all
DNA Repair (Drosophila melanogaster)
Nucleotide Excision Repair (Drosophila melanogaster)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Drosophila melanogaster)
Formation of TC-NER Pre-Incision Complex (Drosophila melanogaster)
RNA Pol II initiates transcription from damaged DNA template (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
Gene Silencing by RNA (Drosophila melanogaster)
Transcriptional regulation by small RNAs (Drosophila melanogaster)
AGO1,2:small RNA complexes interact with chromatin (Drosophila melanogaster)
AGO1,2:miRNA:chromatin:RNA pol II [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
RNA Pol II CTD phosphorylation and interaction with CE (Drosophila melanogaster)
Extrusion of 5'-end of 30 nt long transcript through the pore in Pol II complex (Drosophila melanogaster)
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Phosphorylation (Ser5) of RNA pol II CTD (Drosophila melanogaster)
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Pre-transcription Events (Drosophila melanogaster)
Abortive Initiation After Second Transition (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Abortive Initiation Before Second Transition (Drosophila melanogaster)
Pol II Promoter Escape Complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Abortive initiation after formation of the first phosphodiester bond (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Fall Back to Closed Pre-initiation Complex (Drosophila melanogaster)
pol II closed pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II open pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription Initiation And Promoter Clearance (Drosophila melanogaster)
RNA Polymerase II Promoter Escape (Drosophila melanogaster)
Addition of Nucleotides 5 through 9 on the growing Transcript (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 9 nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Addition of nucleotides 10 and 11 on the growing transcript: Third Transition (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 11 nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 9 nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Addition of nucleotides between position +11 and +30 (Drosophila melanogaster)
Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 11 nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Addition of the third nucleotide on the nascent transcript (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Unwinding DNA for the nascent transcript (Drosophila melanogaster)
pol II transcription complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Unwinding of DNA for the Nascent Transcript: Second Transition (Drosophila melanogaster)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Promoter Opening: First Transition (Drosophila melanogaster)
pol II closed pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II open pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription Initiation (Drosophila melanogaster)
NTP Binds Active Site of RNA Polymerase II (Drosophila melanogaster)
Pol II initiation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymearse II:NTP:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II open pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Newly Formed Phosphodiester Bond Stabilized and PPi Released (Drosophila melanogaster)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Drosophila melanogaster)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Pol II initiation complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymearse II:NTP:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Drosophila melanogaster)
Binding of TFIIE to the growing preinitiation complex (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Formation of the closed pre-initiation complex (Drosophila melanogaster)
pol II closed pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II (unphosphorylated):TFIIF complex [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II transcribes snRNA genes (Drosophila melanogaster)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Drosophila melanogaster)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
POLR2A [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P04052
Reference Genes
BioGPS Gene:32100
ENSEMBL:FBgn0003277
Flybase:FBgn0003277
KEGG Gene (Drosophila melanogaster):Dmel_CG1554
Monarch:32100
NCBI Gene:32100
Reference Transcript
RefSeq:NM_078569.3
Other Identifiers
155027_at
1640764_at
32100
GO:0000428
GO:0001055
GO:0003677
GO:0003824
GO:0003899
GO:0005634
GO:0005654
GO:0005665
GO:0005694
GO:0005700
GO:0005703
GO:0006351
GO:0006366
GO:0016740
GO:0016779
GO:0031981
GO:0034062
GO:0043226
GO:0046872
GO:0140098
Participates
as a component of
RNA Polymerase II holoenzyme complex (unphosphorylated) [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
phospho-p-S2,S7(CTD)-POLR2A [nucleoplasm]
phospho-p-S5,S7(CTD)-POLR2A [nucleoplasm]
phospho-p-S5(CTD)-POLR2A [nucleoplasm]
phospho-Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm]
phospho-p-3S-POLR2A [nucleoplasm]
phospho-p-S2,S5(CTD)-POLR2A [nucleoplasm]
Inferred From
POLR2A [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_511124.1
Flybase
FBgn0003277
PRO
P04052
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