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GTF2B [nucleoplasm]
Stable Identifier
R-DME-65888
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
P29052
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
RNA Polymerase II Pre-transcription Events (Drosophila melanogaster)
Abortive Initiation Before Second Transition (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Pol II Promoter Escape Complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Abortive initiation after formation of the first phosphodiester bond (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Fall Back to Closed Pre-initiation Complex (Drosophila melanogaster)
pol II closed pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
pol II open pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription Initiation And Promoter Clearance (Drosophila melanogaster)
RNA Polymerase II Promoter Escape (Drosophila melanogaster)
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Addition of the third nucleotide on the nascent transcript (Drosophila melanogaster)
pol II transcription complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Unwinding DNA for the nascent transcript (Drosophila melanogaster)
pol II transcription complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Unwinding of DNA for the Nascent Transcript: Second Transition (Drosophila melanogaster)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Promoter Opening: First Transition (Drosophila melanogaster)
pol II closed pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
pol II open pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription Initiation (Drosophila melanogaster)
NTP Binds Active Site of RNA Polymerase II (Drosophila melanogaster)
Pol II initiation complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
pol II open pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Newly Formed Phosphodiester Bond Stabilized and PPi Released (Drosophila melanogaster)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Drosophila melanogaster)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Pol II initiation complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Drosophila melanogaster)
Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Binding of TFIIE to the growing preinitiation complex (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Formation of the closed pre-initiation complex (Drosophila melanogaster)
pol II closed pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II transcribes snRNA genes (Drosophila melanogaster)
CBCAP complex binds 7-methylguanosine cap of snRNA (Drosophila melanogaster)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Drosophila melanogaster)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Integrator complex processes the 3' end of snRNA (Drosophila melanogaster)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Pre-snRNA is elongated and capped with 7-methylguanosine (Drosophila melanogaster)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Drosophila melanogaster)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Drosophila melanogaster)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Drosophila melanogaster)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Drosophila melanogaster)
GTF2B [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P29052
Reference Genes
BioGPS Gene:34430
CTD Gene:34430
ENSEMBL:FBgn0004915
Flybase:FBgn0004915
KEGG Gene (Drosophila melanogaster):Dmel_CG5193
Monarch:34430
NCBI Gene:34430
Reference Transcript
RefSeq:NM_057540.4
RefSeq:NM_001273420.1
Other Identifiers
143536_at
1634172_at
34430
GO:0001174
GO:0003824
GO:0005515
GO:0005634
GO:0006351
GO:0006352
GO:0006367
GO:0016071
GO:0016251
GO:0016407
GO:0016740
GO:0017025
GO:0042789
GO:0043226
GO:0043229
GO:0046872
GO:0051101
GO:0065003
GO:0070897
GO:0097550
GO:0140223
Participates
as a component of
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Drosophila melanogaster)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Drosophila melanogaster)
Pol II Promoter Escape Complex [nucleoplasm] (Drosophila melanogaster)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Drosophila melanogaster)
pol II open pre-initiation complex [nucleoplasm] (Drosophila melanogaster)
Pol II initiation complex [nucleoplasm] (Drosophila melanogaster)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex [nucleoplasm] (Drosophila melanogaster)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Drosophila melanogaster)
as an output of
Abortive initiation after formation of the first phosphodiester bond (Drosophila melanogaster)
Abortive Initiation Before Second Transition (Drosophila melanogaster)
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Drosophila melanogaster)
as an input of
Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Drosophila melanogaster)
Inferred From
GTF2B [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_476888.1
,
NP_001260349.1
Flybase
FBgn0004915
PRO
P29052
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:A8JUV0 SBNO
0.488
2
UniProt:O62531
12
AP-1mu [cytoplasmic vesicle membrane]
(R-DME-351196)
AP-1mu [cytoplasmic vesicle membrane]
(R-DME-351191)
AP-1mu [Golgi membrane]
(R-DME-350813)
AP-1mu [Golgi membrane]
(R-DME-350805)
AP-1mu [lysosomal membrane]
(R-DME-432692)
AP-1mu [lysosomal membrane]
(R-DME-432708)
AP-1mu [trans-Golgi network membrane]
(R-DME-2130404)
AP-1mu [trans-Golgi network membrane]
(R-DME-2130512)
AP-1mu [cytosol]
(R-DME-167700)
AP-1mu [cytosol]
(R-DME-167699)
AP-1mu [plasma membrane]
(R-DME-6806311)
AP-1mu [specific granule membrane]
(R-DME-6799365)
0.488
2
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