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(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
Stable Identifier
R-DME-6790530
Type
Complex
Species
Drosophila melanogaster
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Drosophila melanogaster)
Nucleotide Excision Repair (Drosophila melanogaster)
Global Genome Nucleotide Excision Repair (GG-NER) (Drosophila melanogaster)
Dual Incision in GG-NER (Drosophila melanogaster)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Drosophila melanogaster)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
Gap-filling DNA repair synthesis and ligation in GG-NER (Drosophila melanogaster)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Drosophila melanogaster)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Drosophila melanogaster)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Drosophila melanogaster)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Drosophila melanogaster)
Dual incision in TC-NER (Drosophila melanogaster)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Drosophila melanogaster)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
Gap-filling DNA repair synthesis and ligation in TC-NER (Drosophila melanogaster)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Drosophila melanogaster)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Drosophila melanogaster)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Ghost homologue of (PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm]
(Drosophila melanogaster)
RFC Heteropentamer [nucleoplasm]
(Drosophila melanogaster)
RPA heterotrimer [nucleoplasm]
(Drosophila melanogaster)
Participates
as a component of
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Drosophila melanogaster)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Drosophila melanogaster)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Drosophila melanogaster)
as an output of
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Drosophila melanogaster)
Inferred From
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm]
(Homo sapiens)
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