Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
phospho-Cdk5 [nucleoplasm]
Stable Identifier
R-DME-6805249
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
p-Y15,S159-CDK5, P48609
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
Regulation of TP53 Activity (Drosophila melanogaster)
Regulation of TP53 Activity through Phosphorylation (Drosophila melanogaster)
CDK5 phosphorylates TP53 (Drosophila melanogaster)
p-Y15,S159-CDK5:CDK5R1 (99-307) [nucleoplasm] (Drosophila melanogaster)
phospho-Cdk5 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P48609
Gene Names
Cdk5
Reference Genes
BioGPS Gene:36727 Cdk5
ENSEMBL:FBgn0013762
FlyBase:FBgn0013762
KEGG:dme:Dmel_CG8203 Cdk5
Monarch:36727 Cdk5
NCBI Gene:36727 Cdk5
UCSC:P48609 Cdk5
Reference Transcript
RefSeq:NM_057732.4 Cdk5
Other Identifiers
153451_at
1637085_at
36727
GO:0000166
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0004693
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0006468
GO:0007409
GO:0007629
GO:0008045
GO:0008340
GO:0008344
GO:0008582
GO:0016301
GO:0016533
GO:0016740
GO:0035011
GO:0048489
GO:0051301
GO:0051402
GO:0051642
GO:0051963
GO:0070059
GO:0098542
GO:0106310
GO:0140096
GO:1901987
Participates
as a component of
p-Y15,S159-CDK5:CDK5R1 (99-307) [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
Cdk5 [nucleoplasm]
Inferred From
p-Y15,S159-CDK5 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 15 (in Homo sapiens)
Coordinate
15
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O-phospho-L-serine at 159 (in Homo sapiens)
Coordinate
159
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_477080.1
ENSEMBL
FBgn0013762
,
FBtr0087350
,
FBpp0086483
IntEnz
2.7.11.22
FlyBase
FBgn0013762
PRO
P48609
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P25008
1
CycC [nucleoplasm]
(R-DME-212418)
0.621
4
© 2025
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text