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Mcm10 [nucleoplasm]
Stable Identifier
R-DME-68403
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
MCM10, Q9VIE6
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
G2/M Checkpoints (Drosophila melanogaster)
Activation of ATR in response to replication stress (Drosophila melanogaster)
Activation of claspin (Drosophila melanogaster)
Cdc45:CDK:DDK:Mcm10:Activated claspin:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
Loading of claspin onto DNA during replication origin firing (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
Mitotic G1 phase and G1/S transition (Drosophila melanogaster)
G1/S Transition (Drosophila melanogaster)
Activation of the pre-replicative complex (Drosophila melanogaster)
Cdc45 associates with the pre-replicative complex at the origin (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
Cdt1 is displaced from the pre-replicative complex. (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
MCM10:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
DNA polymerase alpha:primase binds at the origin (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
DNA polymerase epsilon binds at the origin (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Drosophila melanogaster)
MCM10:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
DNA Replication (Drosophila melanogaster)
DNA Replication Pre-Initiation (Drosophila melanogaster)
Activation of the pre-replicative complex (Drosophila melanogaster)
Cdc45 associates with the pre-replicative complex at the origin (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
Cdt1 is displaced from the pre-replicative complex. (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
MCM10:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
DNA polymerase alpha:primase binds at the origin (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
DNA polymerase epsilon binds at the origin (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Drosophila melanogaster)
MCM10:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
Mcm10 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VIE6
Gene Names
Mcm10
Reference Genes
BioGPS Gene:35390 Mcm10
ENSEMBL:FBgn0032929
Flybase:FBgn0032929
KEGG Gene (Drosophila melanogaster):Dmel_CG9241 Mcm10
Monarch:35390 Mcm10
NCBI Gene:35390 Mcm10
Reference Transcript
RefSeq:NM_136253.4 Mcm10
Other Identifiers
155063_at
1638868_at
35390
GO:0000228
GO:0000278
GO:0003674
GO:0003677
GO:0003688
GO:0003690
GO:0003697
GO:0005515
GO:0005634
GO:0005694
GO:0006260
GO:0006270
GO:0012501
GO:0030154
GO:0030261
GO:0031298
GO:0035214
GO:0042023
GO:0043226
GO:0043596
GO:0045678
GO:0045931
GO:0046872
GO:0048856
GO:1901693
Participates
as an input of
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Drosophila melanogaster)
as a component of
MCM10:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Inferred From
MCM10 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_610097.2
Flybase
FBgn0032929
PRO
Q9VIE6
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O96989
1
Cdc45 [nucleoplasm]
(R-DME-68563)
0.524
2
UniProt:Q7JVY2
1
dup [nucleoplasm]
(R-DME-68536)
0.524
2
UniProt:P49735
1
MCM2 [nucleoplasm]
(R-DME-68557)
0.524
2
UniProt:Q24168
1
Orc2 [nucleoplasm]
(R-DME-68405)
0.524
2
UniProt:P05205 HP1
0.524
2
UniProt:P21461
2
SIAH2 [cytosol]
(R-DME-374566)
SIAH1 [cytosol]
(R-DME-374563)
0.488
2
UniProt:Q9VF74 Q9VF74
0.488
2
UniProt:Q960F7
2
CG 2017 [extracellular region]
(R-DME-8863001)
CG 2017 [platelet alpha granule lumen]
(R-DME-8862960)
0.488
2
UniProt:Q7KND8
1
Mad1 [cytosol]
(R-DME-141433)
0.488
2
UniProt:Q86LC7 Q86LC7
0.488
2
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