Reactome | MCM2 [nucleoplasm]

MCM2 [nucleoplasm]

Stable Identifier

R-DME-68557

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

P49735

Locations in the PathwayBrowser for interactor UniProt:Q26454

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External Reference Information

External Reference

UniProt:P49735

Reference Genes

BioGPS Gene:40973

ENSEMBL:FBgn0014861

FlyBase:FBgn0014861

KEGG Gene (Drosophila melanogaster):Dmel_CG7538

Monarch:40973

NCBI Gene:40973

Reference Transcript

RefSeq:NM_057773.4

Other Identifiers

141245_at

1632669_at

40973

GO:0000166

GO:0000228

GO:0000278

GO:0000727

GO:0003677

GO:0003697

GO:0003824

GO:0004386

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005694

GO:0006260

GO:0006268

GO:0006270

GO:0006279

GO:0006281

GO:0006310

GO:0006807

GO:0007049

GO:0016787

GO:0016887

GO:0017116

GO:0022414

GO:0030174

GO:0030261

GO:0032508

GO:0042555

GO:0043138

GO:0043226

GO:0044238

GO:0046872

GO:0051301

GO:0071162

GO:0071704

GO:0140097

GO:0140657

GO:1902975

GO:1905775

Participates

as an output of

Mcm4,6,7 trimer forms and associates with the replication fork (Drosophila melanogaster)

as an input of

MCM2 binds MCM4:MCM6:MCM7 heterotrimer (Drosophila melanogaster)

as a component of

MCM2:MCM4:MCM6:MCM7 [nucleoplasm] (Drosophila melanogaster)

Inferred From

MCM2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_477121.1

Flybase

FBgn0014861

PRO

P49735

PDB

6RAY, 6RAZ, 6RAW, 6RAX

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9V461	1	MCM6 [nucleoplasm] (R-DME-68553)	0.839	13
UniProt:Q26454	1	MCM4 [nucleoplasm] (R-DME-68549)	0.768	9
UniProt:Q9VGW6	1	MCM5 [nucleoplasm] (R-DME-68551)	0.709	9
UniProt:Q9XYU1	1	MCM3 [nucleoplasm] (R-DME-68546)	0.693	11
UniProt:Q9VQY9	1	Psf2 [nucleoplasm] (R-DME-176975)	0.664	4
UniProt:O96989	1	Cdc45 [nucleoplasm] (R-DME-68563)	0.664	6
UniProt:Q9W0I7	1	Psf1 [nucleoplasm] (R-DME-176955)	0.556	3
UniProt:Q9W2V7	1	Psf3 [nucleoplasm] (R-DME-5688046)	0.556	3
UniProt:Q9XYU0	1	MCM7 [nucleoplasm] (R-DME-68555)	0.556	6
UniProt:Q9VBI1	1	Sld5 [nucleoplasm] (R-DME-176963)	0.556	3
UniProt:Q9VIE6	1	Mcm10 [nucleoplasm] (R-DME-68403)	0.524	2

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