Reactome | Cdc45 [nucleoplasm]

Cdc45 [nucleoplasm]

Stable Identifier

R-DME-68563

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

CDC45, O96989

Locations in the PathwayBrowser for interactor UniProt:Q26454

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External Reference Information

External Reference

UniProt:O96989

Gene Names

Cdc45

Reference Genes

BioGPS Gene:31052 Cdc45

ENSEMBL:FBgn0026143

FlyBase:FBgn0026143

KEGG Gene (Drosophila melanogaster):Dmel_CG3658 Cdc45

Monarch:31052 Cdc45

NCBI Gene:31052 Cdc45

UCSC:O96989 Cdc45

Reference Transcript

RefSeq:NM_130524.5 Cdc45

Other Identifiers

154744_at

1632288_at

31052

GO:0000228

GO:0000278

GO:0000727

GO:0003677

GO:0003682

GO:0003688

GO:0003697

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0006260

GO:0006270

GO:0006277

GO:0006281

GO:0006310

GO:0007049

GO:0030261

GO:0031261

GO:0043226

GO:0051301

GO:0065003

GO:0071162

GO:1902977

Participates

as an input of

Cdc45 associates with the pre-replicative complex at the origin (Drosophila melanogaster)

as a component of

CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Drosophila melanogaster)

Inferred From

CDC45 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_569880.1

Flybase

FBgn0026143

PDB

6RAY, 6RAX, 6RAW, 6RAZ

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49735	1	MCM2 [nucleoplasm] (R-DME-68557)	0.664	6
UniProt:Q9XYU1	1	MCM3 [nucleoplasm] (R-DME-68546)	0.527	5
UniProt:Q9VBI1	1	Sld5 [nucleoplasm] (R-DME-176963)	0.527	4
UniProt:Q9VIE6	1	Mcm10 [nucleoplasm] (R-DME-68403)	0.524	2
UniProt:Q9VGW6	1	MCM5 [nucleoplasm] (R-DME-68551)	0.508	4
UniProt:Q26454	1	MCM4 [nucleoplasm] (R-DME-68549)	0.508	4

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