Reactome | CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm]

CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm]

Stable Identifier

R-DME-68564

Type

Complex

Species

Drosophila melanogaster

Compartment

nucleoplasm

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Cdc45 [nucleoplasm] (Drosophila melanogaster)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Drosophila melanogaster)

Participates

as an input of

DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Drosophila melanogaster)
Loading of claspin onto DNA during replication origin firing (Drosophila melanogaster)

as an output of

Cdc45 associates with the pre-replicative complex at the origin (Drosophila melanogaster)

as a component of

CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Drosophila melanogaster)
Cdc45:CDK:DDK:Mcm10:Activated claspin:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Drosophila melanogaster)

Inferred From

CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Homo sapiens)

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