Reactome | Rbp1 [nucleoplasm]

Rbp1 [nucleoplasm]

Stable Identifier

R-DME-72035

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

SRSF3, Q02427

Locations in the PathwayBrowser

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Metabolism of RNA (Drosophila melanogaster)

- Processing of Capped Intron-Containing Pre-mRNA (Drosophila melanogaster)
  - Formation of pre-mRNPs (Drosophila melanogaster)
    - Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
      - shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
      - Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
  - Transport of Mature Transcript to Cytoplasm (Drosophila melanogaster)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Drosophila melanogaster)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Drosophila melanogaster)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Drosophila melanogaster)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
  - mRNA 3'-end processing (Drosophila melanogaster)
    - mRNA Polyadenylation (Drosophila melanogaster)
      - Core CPA complex binds capped pre-mRNA (Drosophila melanogaster)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Drosophila melanogaster)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
      - PP1 dephosphorylates RNA Pol II (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
      - RBBP6 activates CPSF complex (Drosophila melanogaster)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
  - mRNA Splicing (Drosophila melanogaster)
    - mRNA Splicing - Major Pathway (Drosophila melanogaster)
      - Formation of the Spliceosomal B* complex (Drosophila melanogaster)
        
        Spliceosomal B* complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal Bact complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal C complex containing intron lariat (Drosophila melanogaster)
        
        Spliceosomal B* complex [nucleoplasm] (Drosophila melanogaster)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal C complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal C* complex (Drosophila melanogaster)
        
        Spliceosomal C complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
      - Formation of the Spliceosomal P complex and exon ligation (Drosophila melanogaster)
        
        Spliceosomal C* complex [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)
        
        Spliceosomal P complex [nucleoplasm] (Drosophila melanogaster)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Drosophila melanogaster)
        
        Alternative Splicing Factors [nucleoplasm] (Drosophila melanogaster)
        
        shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)
        
        Rbp1 [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q02427

Gene Names

Rbp1

Reference Genes

BioGPS Gene:41294 Rbp1

ENSEMBL:FBgn0260944

FlyBase:FBgn0260944

KEGG:dme:Dmel_CG17136 Rbp1

Monarch:41294 Rbp1

NCBI Gene:41294 Rbp1

UCSC:Q02427 Rbp1

Reference Transcript

Other Identifiers

153149_at

1627812_s_at

1638486_at

41294

GO:0000381

GO:0000398

GO:0000791

GO:0001178

GO:0003676

GO:0003723

GO:0003729

GO:0005634

GO:0006355

GO:0006397

GO:0008380

GO:0010468

GO:0016071

GO:0016607

GO:0031440

GO:0045292

Participates

as a component of

as a member of

shuttling SRSFs [nucleoplasm] (Drosophila melanogaster)

Other forms of this molecule

Rbp1 [nucleoplasm]

Inferred From

SRSF3 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_731510.1, NP_524307.1

ENSEMBL

FBpp0081754, FBtr0082277, FBgn0260944

FlyBase

FBgn0260944

PRO

Q02427

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