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Pi3K21B [cytosol]
Stable Identifier
R-DME-74789
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
PIK3R1, Q7KTZ2
Locations in the PathwayBrowser
Expand all
Developmental Biology (Drosophila melanogaster)
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
RET signaling (Drosophila melanogaster)
p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Drosophila melanogaster)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Drosophila melanogaster)
p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI3K delta [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI3K delta [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Platelet activation, signaling and aggregation (Drosophila melanogaster)
GPVI-mediated activation cascade (Drosophila melanogaster)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Immune System (Drosophila melanogaster)
Cytokine Signaling in Immune system (Drosophila melanogaster)
Signaling by Interleukins (Drosophila melanogaster)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Drosophila melanogaster)
Regulation of signaling by CBL (Drosophila melanogaster)
CBL ubiquitinates PI3K (Drosophila melanogaster)
FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI3K delta [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated (Drosophila melanogaster)
FYN-like kinases:CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI3K delta [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
p85-containing Class 1A PI3Ks [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI3K delta [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
Role of LAT2/NTAL/LAB on calcium mobilization (Drosophila melanogaster)
PI3K associates with phosphorylated GAB2 (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Phosphorylation of PIP2 to PIP3 by PI3K (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
p-10Y-NTAL:p-SHC1:GRB2:SOS:p-3Y-GAB2:PI3K [plasma membrane] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Phospholipid metabolism (Drosophila melanogaster)
PI Metabolism (Drosophila melanogaster)
Synthesis of PIPs at the plasma membrane (Drosophila melanogaster)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Drosophila melanogaster)
PIK3C(1) [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PIK3CD:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Drosophila melanogaster)
PIK3(2) [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PIK3CD:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
ESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI3K:p-ERBB4cyt1 [plasma membrane] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
ESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI3K:p-ERBB4cyt1 [plasma membrane] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Phospho-IRS1/2:PI3K(p85:p110) [plasma membrane] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
RAS:GTP binds PI3K (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
p21 RAS:GTP:PI3K [plasma membrane] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by Erythropoietin (Drosophila melanogaster)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Drosophila melanogaster)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
PI3K alpha, gamma [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PIK3CD:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI3K alpha, gamma [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PIK3CD:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by ALK (Drosophila melanogaster)
PI3K synthesizes PIP3 downstream of ALK (Drosophila melanogaster)
Active ALK:PI3K [plasma membrane] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by EGFR (Drosophila melanogaster)
GAB1 signalosome (Drosophila melanogaster)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Drosophila melanogaster)
EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by ERBB2 (Drosophila melanogaster)
PI3K events in ERBB2 signaling (Drosophila melanogaster)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Drosophila melanogaster)
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by ERBB4 (Drosophila melanogaster)
PI3K events in ERBB4 signaling (Drosophila melanogaster)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Drosophila melanogaster)
PI3K:p-ERBB4cyt1 [plasma membrane] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by FGFR (Drosophila melanogaster)
Signaling by FGFR1 (Drosophila melanogaster)
Downstream signaling of activated FGFR1 (Drosophila melanogaster)
PI-3K cascade:FGFR1 (Drosophila melanogaster)
Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Drosophila melanogaster)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by FGFR2 (Drosophila melanogaster)
Downstream signaling of activated FGFR2 (Drosophila melanogaster)
PI-3K cascade:FGFR2 (Drosophila melanogaster)
Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by FGFR3 (Drosophila melanogaster)
Downstream signaling of activated FGFR3 (Drosophila melanogaster)
PI-3K cascade:FGFR3 (Drosophila melanogaster)
Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Drosophila melanogaster)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by FGFR4 (Drosophila melanogaster)
Downstream signaling of activated FGFR4 (Drosophila melanogaster)
PI-3K cascade:FGFR4 (Drosophila melanogaster)
Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by Insulin receptor (Drosophila melanogaster)
Insulin receptor signalling cascade (Drosophila melanogaster)
IRS-mediated signalling (Drosophila melanogaster)
PI3K Cascade (Drosophila melanogaster)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Drosophila melanogaster)
PI3K-containing complexes [cytosol] (Drosophila melanogaster)
Activated FGFR bound to PI3K [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by PDGF (Drosophila melanogaster)
Downstream signal transduction (Drosophila melanogaster)
PI3-kinase binds to the active receptor (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Drosophila melanogaster)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Drosophila melanogaster)
IGF1R signaling cascade (Drosophila melanogaster)
IRS-related events triggered by IGF1R (Drosophila melanogaster)
IRS-mediated signalling (Drosophila melanogaster)
PI3K Cascade (Drosophila melanogaster)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Drosophila melanogaster)
PI3K-containing complexes [cytosol] (Drosophila melanogaster)
Activated FGFR bound to PI3K [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
p-Y-IRS1,p-Y-IRS2 bind PI3K (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
p-Y-IRS1,p-Y-IRS2:PI3K [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase cycle (Drosophila melanogaster)
CDC42 GTPase cycle (Drosophila melanogaster)
CDC42 GAPs stimulate CDC42 GTPase activity (Drosophila melanogaster)
CDC42 GAPs [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RAC1 GTPase cycle (Drosophila melanogaster)
RAC1 GAPs stimulate RAC1 GTPase activity (Drosophila melanogaster)
RAC1 GAPs [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RAC2 GTPase cycle (Drosophila melanogaster)
RAC2 GAPs stimulate RAC2 GTPase activity (Drosophila melanogaster)
RAC2 GAPs [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RAC3 GTPase cycle (Drosophila melanogaster)
RAC3 GAPs stimulate RAC3 GTPase activity (Drosophila melanogaster)
RAC3 GAPs [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RHOA GTPase cycle (Drosophila melanogaster)
RHOA GAPs stimulate RHOA GTPase activity (Drosophila melanogaster)
RHOA GAPs [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RHOB GTPase cycle (Drosophila melanogaster)
RHOB GAPs stimulate RHOB GTPase activity (Drosophila melanogaster)
RHOB GAPs [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RHOD GTPase cycle (Drosophila melanogaster)
RHOD GAPs stimulate RHOD GTPase activity (Drosophila melanogaster)
RHOD GAPs [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RHOF GTPase cycle (Drosophila melanogaster)
RHOF GAPs stimulate RHOF GTPase activity (Drosophila melanogaster)
RHOF GAPs [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RHOG GTPase cycle (Drosophila melanogaster)
RHOG GAPs stimulate RHOG GTPase activity (Drosophila melanogaster)
RHOG GAPs [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RHOJ GTPase cycle (Drosophila melanogaster)
RHOJ GAPs stimulate RHOJ GTPase activity (Drosophila melanogaster)
RHOJ GAPs [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RHOU GTPase cycle (Drosophila melanogaster)
RHOU binds effectors at the plasma membrane (Drosophila melanogaster)
RHOU effectors [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RHOU:GTP:RHOU effectors [plasma membrane] (Drosophila melanogaster)
RHOU effectors [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RHOV GTPase cycle (Drosophila melanogaster)
RHOV binds effectors at the plasma membrane (Drosophila melanogaster)
RHOV effectors [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
RHOV:GTP:RHOV effectors [plasma membrane] (Drosophila melanogaster)
RHOV effectors [cytosol] (Drosophila melanogaster)
Pi3K21B [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7KTZ2
Gene Names
Pi3K21B
Reference Genes
BioGPS Gene:33203 Pi3K21B
CTD Gene:33203 Pi3K21B
ENSEMBL:FBgn0020622
FlyBase:FBgn0020622
Monarch:33203 Pi3K21B
NCBI Gene:33203 Pi3K21B
UCSC:Q7KTZ2 Pi3K21B
Reference Transcript
RefSeq:NM_057922.4 Pi3K21B
RefSeq:NM_001272888.1 Pi3K21B
Other Identifiers
154995_at
1622909_at
33203
GO:0001784
GO:0003824
GO:0005829
GO:0005942
GO:0005943
GO:0006629
GO:0008286
GO:0008361
GO:0010884
GO:0014065
GO:0016301
GO:0016740
GO:0019900
GO:0035014
GO:0042127
GO:0043491
GO:0043551
GO:0043560
GO:0046854
GO:0046935
GO:0098772
GO:2000252
Participates
as a candidate of
RHOA GAPs [cytosol] (Drosophila melanogaster)
RHOV effectors [cytosol] (Drosophila melanogaster)
CDC42 GAPs [cytosol] (Drosophila melanogaster)
RAC2 GAPs [cytosol] (Drosophila melanogaster)
RHOD GAPs [cytosol] (Drosophila melanogaster)
RAC1 GAPs [cytosol] (Drosophila melanogaster)
RHOF GAPs [cytosol] (Drosophila melanogaster)
RHOB GAPs [cytosol] (Drosophila melanogaster)
RHOG GAPs [cytosol] (Drosophila melanogaster)
RHOJ GAPs [cytosol] (Drosophila melanogaster)
RAC3 GAPs [cytosol] (Drosophila melanogaster)
as a member of
RHOU effectors [cytosol] (Drosophila melanogaster)
as a component of
PIK3CD:PIK3R1 [cytosol] (Drosophila melanogaster)
Active FLT3:GRB2:p-Y-GAB2:PIK3R1 [cytosol] (Drosophila melanogaster)
PI3K delta [cytosol] (Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol] (Drosophila melanogaster)
PIK3CA:PIK3R1 [cytosol] (Drosophila melanogaster)
PI3K [cytosol] (Drosophila melanogaster)
as an input of
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Drosophila melanogaster)
Other forms of this molecule
Pi3K21B [cytosol]
Pi3K21B [cytosol]
Pi3K21B [cytosol]
Pi3K21B [cytosol]
Pi3K21B [cytosol]
Pi3K21B [plasma membrane]
Inferred From
PI3K-regulatory subunits [cytosol]
(Homo sapiens)
PI3K-regulatory subunit [cytosol]
(Homo sapiens)
PIK3R1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001259817.1
,
NP_477270.2
ENSEMBL
FBtr0331208
,
FBpp0303635
,
FBpp0303632
,
FBtr0331205
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